App-Quantinova.ai

Absence of Hspb1 Increases Endothelium-dependent Protease Activated Receptor 2-mediated Vasorelaxation in a Female but Not Male Arteries

Mahmoud Saifeddine - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Acetylcholine

Vascular Smooth Muscle Cells Retain Cell Physiological Abnormalities as a Function of Underlying Type-2 Diabetes.

Terrance Yau - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Angiology

Coronary Artery Disease

Phenylephrine

Unexpected Role of PCSK9 in Human Pluripotent Stem Cells and Their Differentiation

Amandine Caillaud - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Induced Pluripotent Stem Cell Based Drug Screening Platform for Vascular Abnormalities in Patients With Elastin Insufficiency

Rahul Agrawal - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Rapacan

Transient Neonatal Exposure to High Oxygen Levels is Associated With Impaired Ischemia-induced Neovascularization During Adulthood

Sylvie Dussault - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Vasodilation dysfunction

Superoxide dismutase

Renin-Angiotensin Axis in Hematopoietic Stem/Progenitor Cells Predicts Vascular Dysfunction and Diabetic Retinopathy

Rehae C. Miller - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Diabetic retinopathy

Fluorescein sodium

Cardioprotection by GLP-1(28-36) is Mediated by ATP-Dependent Activation of Soluble Adenylyl Cyclase in Coronary Vascular Cells

Dhanwantee Mundil - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

Probenecid

Doxorubicin Provokes Maladaptive Autophagy and Necrotic Cell Death of Cardiac Myocytes by Disrupting Mitochondrial Respiration Chain Complex IV

Hongying Gang - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

Doxorubicin

PI3K? Deletion in Cardiomyocytes Causes Maintained Mitochondrial Membrane Potential and Blocks Necrotic Cell Death in Ischemia/Reperfusion Injury

Pavel Zhabyeyev - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

Tamoxifen

Profiling the Altered Cellular and Secreted Proteome of Cardiac Fibroblasts in Hypoxia Through Label-free Quantitation

Hongbo Guo - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemic injury

N/A

Identification of Resident Cardiac Cell-type Enriched Proteomes Reveals Novel Cardiac Fibroblast Markers in Myocardial Infarct Zones

Kathryn Lipsett - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertrophic cardiomyopathy

N/A

Plin2 Protects Against Palmitate-mediated Lipotoxicity in a Cardiomyoblast Cell Line

Taha Haffar - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Palmitic acid

Cardiac Hypertrophy in Neonates With Congenital Heart Disease Delays Maturational Changes in Cardiac Energy Metabolism via Decreased Mitochondrial Acetylation

Liyan Zhang - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congenital heart disease

N/A

Inhibition of Mitochondrial Calcium Uptake in the Heart Does Not Compromise Cardiac Energetics or Function Due to a Preferential Increase in Fatty Acid Oxidation During Increased Cardiac Work

Jennifer Kwong - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Isoproterenol

Snf1-related Kinase Improves Cardiac Mitochondrial Efficiency by Decreasing Mitochondrial Uncoupling

Hsiang-Chun Chang - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemic cardiomyopathy

Palmitic acid

Collagen Biomaterial Enhances Cd34+ Cell Function Through Mir-21b

Aleksandra Ostojic - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

DE-074

Circulating Nucleoside and Bile Acid Intermediary Metabolites Are Associated With Recurrent Ischemic Events in Acute Coronary Syndrome

Jordan Morningstar - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Acute Coronary Syndromes

intrarectal sodium taurocholate

Do Screening Electrocardiograms in a Tertiary Bariatric Program Alter Patient Management? A Retrospective Cohort Study

Tyler James - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Progressive cardiac conduction defect

N/A

Quantity and Quality of Visceral Adipose Tissues: Their Roles into Comorbidities Related With Severe Obesity and Comorbidities Resolution After Bariatric Surgery

Marie-Eve Piche - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Sleep apnoea

N/A

Substitution of Dietary Saturated Fatty Acids With Omega-6 Polyunsaturated Fatty Acids Decreases LDL ApoB-100 Production Rate in Men With Dyslipidemia Associated With Insulin-Resistance

Andre J Tremblay - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Dyslipidemia

N/A

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