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Mutation-specific siRNA Knockdown of GJB2 − Potential gene therapy for Keratitis-ichthyosis-deafness Syndrome

M. Lee - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Keratitis ichthyosis deafness

N/A

Mutations in KLHL24 add to the molecular heterogeneity of epidermolysis bullosa simplex

J.Y.W. Lee - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Epidermolysis bullosa

methionine

Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants

C. Wong - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

TALEN-mediated gene editing of keratinocyte stem cells for a novel ex vivo epidermolytic ichthyosis therapy

O. March - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Bullous congenital ichthyosiform erythroderma

N/A

Utilizing 3D dermal equivalents to evaluate effects of carob seed extract on dermal maturation

N. Fullard - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Carob

Novel diagnostic approach in detecting skin infection: Identification of bacterial-specific volatile organic compounds in bacterial biofilms on human cutaneous wound models

M. Ashrafi - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Dissecting the effects of a stress-related mediator, corticotropin releasing hormone on skin and mucosal type mast cells biology in situ

K. Sugawara - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Dermatology

Atopic Dermatitis

Corticotropin

The impact of environmental pressures on cellular bioenergetics in ageing human skin

M.J. Jackson - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Tuberculosis

Nicotinamide

Dual IL-17A and IL-17F inhibition with bimekizumab provides evidence for IL-17F contribution to immune-mediated inflammatory skin response

A. Maroof - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Dermatology

Psoriasis

bimekizumab

Impact of chronic sun exposure on the elastic fiber network of African-American and Caucasian skin

A. Langton - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Fluoxetine promotes human hair follicle pigmentation: A new anti-greying strategy

J. Gherardini - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Corticotropin

Molecular basis of hair follicle donor dominance in androgenetic alopecia and sexual dimorphism of the skin

Y. Doucet - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Catalytic-dependent and -independent activities of Polycomb repressive complex 1 differentially regulate skin stem cell specification

I. Cohen - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium

I. Malashchuk - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Exploring the role of microRNAs in alopecia areata

D. Broadley - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Minoxidil

Olfactory receptor stimulation promotes human hair growth

J. Chéret - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Minoxidil

The PPARα ligand, 10-hydroxyoctadecanoic acid, reduces facial pore size and pigmentation in normal skin

R. Schuetz - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

Potential increase of endogenous double-stranded RNA in psoriasis and its role in NB-UVB induced psoriasis clearance

S. Al-Hashimi - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2023

Therapeutic Area

Disease

Drug/Treatment

Dermatology

Psoriasis

Adenosine

HLA class II-restricted CD8+ T cells contribute to the promiscuous immune response in dapsone hypersensitive patients

Q. Zhao - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

Dapsone

Tissue differentiation of IL26+ TH17 cells into IL-17A producers via an epithelial crosstalk

A. Fries - International Investigative Dermatology/Society for Investigative Dermatology (IID/SID) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

Interleukin

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