App-Quantinova.ai

Interaction of γδ TCR with the WC1 hybrid co-receptor/pathogen recognition receptor in cattle.

Alexandria Gillespie - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

Role of SLAMF immunoregulatory molecules in MS disease processes

Jordan S Mizrahi - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Multiple Sclerosis

N/A

Association of baseline cytokine levels with anti-tumour necrosis factor treatment response in rheumatoid arthritis

David S Gibson - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Rheumatoid arthritis

N/A

Culturally appropriate advisory and governance oversight for the study of rheumatic fever and rheumatic heart disease in New Zealand

Dianne Sika-Paotonu - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Rheumatic heart disease

Interleukin

TCR recognition is a mediator in the control of HIV infection by CD8 T cells

Rodrigo A Matus Nicodemos - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Human immunodeficiency virus infection

N/A

Dissection of CD8+ T cell immunodominance hierarchy in human influenza virus infection

Sneha Ashok Sant - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Influenza

N/A

Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Linda Wooldridge - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Multiple Sclerosis

N/A

Early-life respiratory bacterial infection-induced chronic lung disease is driven by a novel TLR2/IL-13/miR-21/PI3K-dependent, but MyD88-independent signalling pathway

Malcolm Ronald Starkey - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Chronic obstructive pulmonary disease

N/A

The dual roles of membrane and soluble forms of gC1qR and C1q in the breast cancer microenvironment.

Evelyn Kandov - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

Fibrinogen (IV)

CD73 expression in cancer-associated fibroblasts exacerbates immune suppression and promotes tumor progression via augmenting adenosine accumulation in the tumor microenvironment

Miao Yu - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

Adenosine

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Nathalie Niyonzima - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

A single nucleotide polymorphism in an AP2 transcription factor encoded in the malaria-causing Plasmodium berghei alters the development of host immunity

Patrick William Sheehan - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Cerebral malaria

chloroquine

The role of CD40 in calcitonin gene related protein (CGRP) mediated antiviral effect in glial cells

Eliza Grlickova-Duzevik - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Peripheral Nervous System

Peripheral neuropathy

Calcitonin

Polymorphisms in FcγRII (CD32) mediate abnormal antibody half-life in NOD SCID mice and reduce antibody-mediated tumour cell deletion.

Robert J Oldham - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

hCD20

Dynamic modulation of cortical actin at the immunological synapse controls lytic granule secretion in cytotoxic T lymphocytes

Senta Kapnick - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

Phosphatidylinositol

Canonical and cross-reactive binding of NK cell inhibitory receptors to HLA-C allotypes is dictated by peptides bound to HLA-C

Malcolm John Wyness Sim - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

Development of new immune reagents for swine health, vaccine and disease studies

Jean Nepomuscene Manirarora - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

Interferon Gamma

Early morphine exposure reduced viral burden in the periphery and induced regional difference in brains of LP-BM5 MAIDS model

Alexa A Wakley - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Acquired immunodeficiency syndrome

Morphine

Gp120 transgenic mice infected with LP-BM5 virus show exacerbated symptoms compared to LP-BM5 murine AIDS alone

Taxiarhia J Arabatzis - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Acquired immunodeficiency syndrome

N/A

Butyrophilin (BTN) molecules control γδ T cells in tissue epithelia

David A. Rhodes - American Association of Immunologists (AAI) , 2018

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

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45280 Abstracts