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: Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Researchers

Presenter

  • Linda Wooldridge

Principal Investigators

  • James Alexander Pearson

  • Stephanie Gras

  • Hugo van den Berg

  • Anya Lissina

  • Sian Llewellyn-Lacey

  • Mark Willis

  • Tamsin Dockree

  • James E McLaren

  • Julia Ekeruche-Makinde

  • Emma Gostick

  • Neil Robertson

  • Jamie Rossjohn

  • Scott R Burrows

  • David Price

  • Susan Wong

  • Mark Peakman

  • Ania Skowera

  • Matthew Clement

Medical Centers

  • University of Bristol, Bristol, United Kingdom

  • Yale Univ

  • Monash Univ., Australia

  • Warwick University, Coventry, United Kingdom

  • Cardiff Univ., United Kingdom

  • Imperial College, London, United Kingdom

  • QIMR Berghofer Medical Research Institute, Brisbane, Sydney, Australia

  • Kings College London, London, United Kingdom

Locations

  • United Kingdom

  • Australia

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Multiple Sclerosis

  • Diabetes

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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