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45280 Abstracts

Intra-articular CNTX-4975 for osteoarthritis knee pain: subgroup and post hoc analyses of a randomized phase 2 study

R.M. Stevens - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

Capsaicin

Safety and efficacy of six months' open label extension post-RCT using the novel cathepsin K inhibitor MIV-711 in patients with knee osteoarthritis

P.G. Conaghan - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

MIV711

Procedure pain associated with intra-articular injection of CNTX-4975 for management of painful osteoarthritis of the knee varies with cooling

R.M. Stevens - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

Epinephrine

Bilateral intra-articular injection of CNTX-4975 for management of painful osteoarthritis of the knee: results at 6 weeks from an open-label trial

R.M. Stevens - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

Epinephrine

The association of monocytes and Tregs with disease activity in rheumatoid arthritis

Amanda Jayne Eakin - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Rheumatoid arthritis

N/A

Prime and Target Immunization Protects Against Liver-Stage Malaria

Anita Gola - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Malaria

N/A

Small molecule drug inhibition of PD-1 transcription is as effective as anti-PD-1 biologic blockade in cancer therapy

Christopher E Rudd - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Expression of the TNF-family cytokine TL1A (TNFSF15) by renal CX3CR1+ resident mononuclear phagocytic cells and role of TL1A in autoimmune nephritis

Nathan Richoz - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Nephrology

Lupus

N/A

A viral immunoevasin controls innate immunity by targeting the prototypical natural killer cell receptor family (NK1.1/NKR-P1)

James R Carlyle - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Cytomegalovirus infection

N/A

Knockout validation of antibodies to Ki67: a marker for cellular proliferation

Hanna S Dreja - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

N/A

Microbiota-independent mechanisms shape Th17 homeostatic responses at the oral barrier.

Nicolas Dutzan - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Immunology Antibody Validation: PTEN a target case in the use of human KO cell lines for antibody validation

Julie S Ayton - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Enhancement of antigen-specific Natural Killer cell ‘memory’ by removal of a viral innate immune signalling inhibitor

Hongwei Ren - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Influenza

N/A

A whole genome mouse siRNA screen to identify novel genes involved in lipid antigen presentation

Shilpi Chandra - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

APOBEC gene family expression and hallmarks in chronic lymphocytic leukemia

Charles C Chu - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Chronic Lymphocytic Leukemia

N/A

The RNA transcriptome of in vivo influenza virus infection reveals unique gene expression profiles in type 2 alveolar epithelial cells.

Christopher Stairiker - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Influenza

Interferon

Unique properties of GC B cells permit optimal BCR affinity discrimination

Kihyuck Kwak - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Bcl11b, a novel GATA3-interacting protein, regulates T-helper-2-cell differentiation and function

Difeng Fang - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

B cell lymphomas

IL-4

A novel image cytometric analysis method for T cell-mediated cytotoxicity of 3D tumor spheroids

Leo Chan - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Breast cancer

N/A

The genetics and expression of canine antigen receptors analysed with a novel RNA-seq strategy.

Jolyon N E Martin - American Association of Immunologists (AAI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Lymphomas

N/A

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