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: Small molecule drug inhibition of PD-1 transcription is as effective as anti-PD-1 biologic blockade in cancer therapy

Researchers

Presenter

  • Christopher E Rudd

Principal Investigators

  • David Rothstein

  • Alison Taylor

Medical Centers

  • Division of Immunology-Cell Therapy, Research Center Maisonneuve-Rosemont Hospital (CR-HMR), Montreal, Quebec H1T 2M4, Canada, Canada

  • Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

  • Leeds Institute of Cancer & Pathology, St James’s University Hospital, Beckett Street LEEDS LS9 7TF, United Kingdom

Locations

  • Canada

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

  • Lymphomas

  • Melanoma

Biomarkers

  • Cluster of Differentiation 107 Antigen-Like Family Member A

  • Cluster of differentiation 8A

  • Granzyme B

  • tumor-infiltrating lymphocytes

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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