App-Quantinova.ai

Impact of Right Ventricular Longitudinal Strain at Rest and Under Dobutamine Stress on Outcome in Low-Flow, Low-Gradient Aortic stenosis -Results from the TOPAS Study

Marie-Annick Clavel - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Myocardial infarction

Dobutamine

Remodeling of Fibroblast K+ Channels in Atrial Profibrillatory Pathologies

Xiao-Yan Qi - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

N/A

Exchange Protein Directly Activated by cAMP (Epac) and Combined Transcriptional/Translational Pathways Underlie Slow Delayed Rectifier Current Remodeling by Sustained Beta-Adrenergic Activation

Ling Xiao - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

Isoproterenol

Exome Sequencing Identifies a Novel Variant in ACTC1 Segregating in a Family with Atrial Septal Defects

Ross McLoed - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Atrial septal defect

N/A

Downregulation of the Angiomir-126 Contributes to the Failing Right Ventricle in Pulmonary Arterial Hypertension

Augan Camille - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Pulmonary arterial hypertension

N/A

Diagnosing Heparin Induced Thrombocytopenia Post Cardiac Surgery

Cardiac Sciences Program - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Thrombocytopenia

Heparin

Arteriogenesis is Impaired in CSEKO Mouse Hind Limb Ischemia Due to Attenuated Expression of Chemokines and Cytokines

Rui Wang - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Angiology

Acute limb ischemia

Interleukin

PI3K? is Required for Recovery from Transient Cre/tamoxifen Induced Cardiotoxicity

Seyyed M. R. Kazemi-Bajestani - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Systolic dysfunction

Phosphatidylinositol

Cardiac Fingerprint of Autophagy Gene Expression Following Ischemia-Reperfusion Injury

Bobby Yanagawa - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

Cardioplegic

Signaling via PI3K? and PI3K? and Increased Glucose Oxidation Contribute to the Marked Protection Against Ischemia/Reperfusion Injury in PI3K?DN Hearts

Wang Wang - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

Phosphatidylinositol

Transgenic Mice Lacking Sirt1 or Sirt1 Catalytic Activity Exhibit Greater Susceptibility to Pulmonary Hypertension in Response to Chronic Hypoxia

Yupu Deng - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Pulmonary arterial hypertension

N/A

Novel Index Using Doppler Timing Intervals for Distinguishing True Severe Stenosis from Pseudo-Severe Stenosis in Low-Flow Low-Gradient Aortic Stenosis by Resting Transthoracic Echocardiography

Adrian A Chong - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Aortic stenosis

Dobutamine

GLP-1[28-36] Exerts Direct Cardioprotective Effects, Activating Pro-Survival Kinases and Soluble Adenylyl Cyclase

Sanja Beca - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

N/A

Impact of Global Left Ventricular Longitudinal Strain on Outcomes in Low-Flow, Low-Gradient Aortic Stenosis

CRIUCPQ - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Coronary Artery Disease

Dobutamine

Functional Enhancement of Circulating Angiogenic Cells Cultured on a Collagen Biomaterial Using the Cysteine-rich Angiogenic Inducer 61 (CYR-61) Protein

Branka Vulesevic - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

N/A

DE-074

Repeated Paroxysmal Atrial Fibrillation Episodes Remodel Ionic Currents and Promote Atrial Fibrillation in Dogs

XiaoYan Qi - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Arrhythmia

N/A

Potential Role of PDGF-Activated JAK/STAT Pathway in CHF-Related Atrial-Selective Fibrotic Remodeling

Sirirat Surinkaew - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

Becaplermin

BRCA1 Reduces Oxidative Stress, Up-Regulates Nitric Oxide Production, and Attenuates Endothelial Cell Apoptosis: A Novel Target for Reduced Endothelial Dysfunction

Praphulla Shukla - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Vasodilation dysfunction

Nitric oxide

Lysophosphatidylcholine Derived From Lp-PLA2 Promotes the Mineralization of the Aortic Valve

Marie-Chloe Boulanger - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Calcific Aortic Valve Disease

N/A

Risk Factors and Outcomes of Necrotizing Enterocolitis (NEC) in Congenital Heart Disease Patients Post-intervention

Cedric Manlhiot - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Hypoplastic left heart syndrome

N/A

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