App-Quantinova.ai

CD36 Signaling Regulates Autophagy to Limit Macrophage Cholesterol Accumulation

Esther Mak - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Atherosclerotic lesions

N/A

Soluble CD40 Ligand Reverses the Inhibitory Effect of Early Endothelial Progenitor Cells on Platelet Aggregation

Ahmed Hachem - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

N/A

Potential Protective Effects of Semaphorin3A on Macrophage Function

Talin Ebrahimian - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

ICAM-1

The Interaction of Chest Compression Rates with the Impedance Threshold Device and Association with Survival Following Out-of-hospital Cardiac Arrest.

Danielle Guffey - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Cardiac arrest

N/A

HDL Mimetic Peptides ATI-5261 and CS-6253 Induce ABCA1 Oligomerization, Cellular Cholesterol Efflux and Generate Nascent HDL-Like Lipoproteins.

John Bielicki - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

N/A

Mifepristone

Saturated Fat Ingestion Impairs HDL Function in Diabetes

Christina Schall - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Coronary Artery Disease

N/A

Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) is Elevated in Acute Coronary Syndromes and Resides Predominantly in LDL.

Hong Choi - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Stable coronary artery disease

N/A

Niacin Beneficially Alters the Secretion of Intestinal-derived TRL and HDL in a Rat Model of Insulin Resistance

Faye Borthwick - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

N/A

Niacor

Novel Role of Bim in the Regulation of Allogeneic T-Cell Activation and Development of Transplant Vasculopathy

Winnie Enns - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Transplant rejection

N/A

MEK/ERK Inhibition Corrects the Defect in VLDL Assembly and Secretion in HepG2 Cells via Activation of Cell Death-Inducing DFFA-Like Effector B (Cide B), ApoCIII and Lipin-1

Wei Qiu - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Giant cell arteritis

Glucocorticoid

Detailed Characterization of the Role of the Epidermal Growth Factor Precursor Homology Domain A of the Low-density Lipoprotein Receptor in Proprotein Convertase Subtilisin/kexin-type 9 Binding

Ayinuer Adijiang - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

N/A

Inhibition of Four- and- a- Half LIM Domain Protein-2 Decreases Atherosclerosis in Apoe -/- Mice model: Role of Immune T- Cells

Maryam Heidari - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Coronary Artery Disease

ICAM-1

Omega-3 Supplementation Does Not Affect Inflammatory Gene Expression in the Small Intestine of Patients with Type 2 Diabetes

Patrick Couture - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Angiology

Coronary Artery Disease

Streptozotocin

Treatment of Omega-3 Nutritional Deficiency Improves Cardiovascular Disease Risk Factors: Results of the Randomized, Double-Blind, Placebo-Controlled VASCAZEN-REVEAL Trial

Abbas Ali - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

N/A

Icosapent ethyl

Shear Stress-induced Atherosclerotic Plaque Regression is Reversed by Regulation of Macrophage Mobility via Matrix Metalloproteinase Inhibition

Talin Ebrahimian - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

Doxycycline

Nuclear Factor-?B Is Involved in Platelet CD40 Signaling and Activation

Daniel Yacoub - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

N/A

BAY117082

Assessing the Impact of Cardiovascular Disease-Related Genetic Variation on Clinical Cognitive Impairment

Christopher T Johansen - American Heart Association (AHA) , 2012

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Dyslipidemia

N/A

Docosahexaenoic Acid-Enriched and Oleic Acid-Enriched Canola Oils Reduce Whole Blood Nuclear Factor Kappa-B Gene Expression in Men and Women with Abdominal Obesity

Patrick Couture - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Metabolic syndrome

Docosahexaenoic acid

Basal Peripheral Arterial Blood Flow Increases Concomitantly with Decreased Cardiopulmonary Reserve and Biomarkers Activation in Patients with Heart Failure and Preserved Ejection Fraction

Francois Harel - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Heart failure with preserved ejection fraction

Prostaglandin

Total Circulating Adiponectin Levels and its Receptors are Associated with Histological and Immunohistochemical Features of Carotid Plaque Instability

Robert J. Doonan - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

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