App-Quantinova.ai

Single-Cell Isolation and Analysis of Viable Proliferating Macrophages From Atherosclerotic Plaques

Sherine Ensan - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Atherosclerotic lesions

Hyaluronidase

Homotypic Interactions and Networking Among Vascular Smooth Muscle Cells Are Mediated by a Transforming Growth Factor-?-Cadherin-11 Axis

Hao Yin - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

N/A

Early Pathogenesis of Murine Aortic Valve Disease is Marked by Versican-Rich Proteoglycan Synthesis

Jung-Woo Kwon - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Bicuspid aortic valve

N/A

Development of a Novel Antithrombotic Therapy Targeting Platelet GPIb?: Assessment of Anfibatide In Vitro and in Phase I Clinical Trial

Adili Reheman - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Atherothrombosis

Anfibatide

The Role of FHL2 in Mechanically Regulated Valve Interstitial Cell Osteogenic Differentiation

Jan-Hung Chen - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Calcific Aortic Valve Disease

Alkaline phosphatase

Enhanced Expression Of Epithelial Sodium Channels (ENaC) Causes Salt-induced Hypertension In Mice Through Inhibition Of The ?2-isoform Of Na+, K+-atpase

Xiaohong Hou - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertension

Benzamil

Mutagenic Gene Trapping to Study Novel Genes in Zebrafish Cardiovascular Development

Shahram Eisa-Beygi - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Obstetrics/Gynecology

PDGFRA rearrangement

Codeine

Generation of Oxidized Phosphatidylcholines During Hypoxia-Reoxygenation Triggers Cell Death of Postnatal Cardiac Myocytes

Victoria Margulets - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Hypercholesterolemia Inhibits LPS-Induced CCR7-Dependent Reverse Transmigration of Arterial Intimal Dendritic Cells.

Eric Gracey - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Atherosclerotic lesions

N/A

High-Throughput Analysis of Compounds Targeting Zebrafish Angiogenesis and Vascular Development

Suzan El-Rass - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Solid malignancies

indirubin

Neutrophil Extracellular Traps Promote Thrombin Generation Through Platelet-Dependent and -Independent Mechanisms

Trang Vu - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Sepsis

Evithrom

Osteogenic Factors Regulate Vascular Function Through Reactive Oxygen Species And Toll-Like Receptor 4 Activation: Role In Hypertension.

Rheure A Lopes - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Vasodilation dysfunction

N-acetylcysteine

Inflammatory Cytokines Reduce Thrombin Activatable Fibrinolysis Inhibitor Protein Levels in HepG2 Cells via TTP-Mediated Destabilization of TAFI mRNA

Michael B Boffa - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

N/A

Evithrom

Characterization of Cell Membrane Microdomains Facilitating HDL Biogenesis

Isabelle Ruel - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

LT 02

Lung Cancer Chemotherapy Agents Increase Procoagulant Activity via Protein Disulfide Isomerase-Dependent Tissue Factor Decryption

Laura Swystun - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Non Small Cell Lung cancer

Phosphatidylserine

A Novel High-Throughput Whole Blood Immuno-Counting Assay is Useful in the Assessment of Platelet Responses to Antiplatelet Therapy

Natalia Dovlatova - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Obstetrics/Gynecology

Twin-reversed arterial perfusion

Epinephrine

Androgen Deprivation Therapy-Induced Weight Gain and Atherosclerosis in Prostate Cancer: Differences Between Orchiectomy, GnRH Agonist and Antagonist

Sarah N Hopmans - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Coronary Artery Disease

Leuprolide acetate

Nobiletin Reduces Intestinal Lipoprotein Production in LDL Receptor-Null Mice With Diet-Induced Insulin Resistance

Brian G Sutherland - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Fatty Liver Disease

VLTS-934

ApoB-Lipoprotein Association With Insulin Resistance and Hyperinsulinemia: is Activation of the IL-1? System Involved?

Simon Bissonnette - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Type 2 diabetes mellitus

Interleukin

Nutrigenomic Screening of Functional Foods Regulating Gluconeogenesis: A Zebrafish Pilot Study

Youdong Wang - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Type 2 diabetes mellitus

N/A

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