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Targeted Temperature Management After Cardiac Arrest: The Montreal Heart Institute experience

Laura Dominguez Perez - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Cardiac arrest

N/A

FGF2 Isoform-selective as well as Non-selective Signals Protect Cardiomyocytes from Doxorubicin-induced Cell Death

Barbara E Nickel - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Cardiotoxicity

Doxorubicin

Human Aortic Valve Interstitial Cells Exhibit Decreased Cholesterol Efflux Associated with Hypo- ?1-nascent HDL Particles

Adel Schwertani - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Aortic stenosis

N/A

miRNA Targeting of Oxysterol Binding Protein-like 6 (OSBPL6) Regulates Cholesterol Trafficking and Efflux

Elizabeth Hennessy - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Tissue Inhibitor of Matrix Metalloproteinase-3 (TIMP3) Provides Beneficial Effects Post-MI by Promoting Angiogenesis

Pu Zhang - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Myocardial infarction

TIMP-3 secretion inducer

Semaphorin3A Reduces Atherosclerotic Plaque Formation in ApoE Knock Out Mice Through Regulation of M2 Type Macrophage Migration

Maryam Heidari - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Therapeutic Immunization with an Antiglycosaminoglycan Antibody Reduces Atherosclerotic Lesion Progression in Apolipoprotein E-Deficient Mice

Victor Brito - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Atherosclerotic lesions

Chondroitin sulfate

Telomere-based Assessment of Biological Age in Patients with Advanced Vascular Disease

Oula Akawi - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Characterization of the I4399M Variant of Apolipoprotein(a): Implications for Altered Prothrombotic Properties of Lipoprotein(a)

Corey Scipione - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

methionine

Lymph is a Vehicle for Extracellular Vesicles in Mice

Nicolas Tessandier - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Graft-Derived IL-6 Amplifies Proliferation and Survival of Effector T Cells that Drive Alloimmune-Mediated Vascular Rejection

Kevin Rey - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

N/A

Elucidating the Genetic Determinants of Extreme High-density Lipoprotein Phenotypes Using Next-generation Sequencing

Jian Wang - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Dyslipidemia

N/A

Novel Chimeric Anti-proteoglycan Antibody Inhibits Arterial Retention of Proatherogenic Lipoproteins in a Rat Model of Insulin Resistance

Rabban Mangat - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Coronary Artery Disease

Chondroitin sulfate

Achieving Multiple Lifestyle Behaviour Targets Reduces the Risk of Hypertension in Adolescents

Valerie Carson - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertension

N/A

Identifying Risk Profiles for Sedentary Behavior in Youth Using Recursive Partitioning Based on Individual, Familial, and Neighborhood Environment Factors

Gisele Contreras - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Obesity

N/A

Risk of Mortality According to Burden of Atrial Fibrillation: Results From a 60-year Cohort Study

Mahmoud Tourabi - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Arrhythmia

N/A

Exomechip Meta-analysis of 526,508 Individuals From Five Ancestries Identifies Coding Variation in MC4R and KSR2 Associated with Body Mass Index

Valerie Turcot - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Type 2 diabetes mellitus

N/A

Impaired Autonomic Control of Heart Rate at Rest and Slower Post-exercise Heart Rate Kinetics in Children with Congenital Heart Defects

Stephanie Fusnik - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ventricular septal defect

Epoch

Muscle Metaboreflex Regulation of Arterial Blood Pressure in Children with Congenital Heart Defects

Stephanie Fusnik - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ventricular septal defect

N/A

The Subgingival Microbiome, Systemic Inflammation and Insulin Resistance

Alexander Breskin - American Heart Association (AHA) , 2016

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Systemic inflammation

ILS-969

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