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374 2016 BCVS : FGF2 Isoform-selective as well as Non-selective Signals Protect Cardiomyocytes from Doxorubicin-induced Cell Death

Researchers

Presenter

  • Barbara E Nickel

Principal Investigators

  • Robert R Fandrich

  • Lorrie A Kirshenbaum

  • Peter A Cattini

  • Elissavet Kardami

Medical Centers

  • Univ of Manitoba, Dept of Physiology and Pathophysiology, Winnipeg, MB, Canada

  • Inst of Cardiovascular Sciences, Winnipeg, MB, Canada

  • Univ of Manitoba, Dept of Human Anatomy and Cell Sciences, Winnipeg, MB, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Cardiotoxicity

  • Breast cancer

  • Solid malignancies

Biomarkers

  • AMP-activated protein kinase

  • Lactate dehydrogenase

  • Sequestosome-1

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • Doxorubicin

  • Rapacan

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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