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45280 Abstracts

Inhibition of VEGF signalling mitigates the hereditary haemorrhagic telangiectasia-like phenotype in endoglin mutant zebrafish

Ryan Snodgrass - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

IgM and IgG anti-oxidised low-density lipoprotein antibodies predict protective atherosclerotic characterstics on cardiac ct: a substudy of the scottish computed tomography of the heart (SCOT-HEART) trial

Adam Hartley - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Intravital investigations of the role of IL-36 in mediating age and gender specific changes in the injured beating coronary microcirculation

Juma El-awaisi - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Interleukin

Using zebrafish embryos to identify genes that regulate endothelial proliferation

George Bowley - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Image-based computatinoal simulations of foetal heart function to understand congenital malformations and foetal heart intervention

Choon Hwai Yap - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Aortic stenosis

N/A

The role of parasympathetic nervous system in the infarct-limiting effect of SGLT2 inhibitors

Maryna Basalay - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Ischemia-reperfusion injury

MDT010

RNA binding protein multiple splicing (RBPMS) drives a contractile splicing network in human embryonic stem cell derived vascular smooth muscle cells

Aishwarya Jacob - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Angiology

Calcified vascular disease

Doxycycline

The opposing effects of chronic interleukin-1β on TIE2:TIE1 ratio and angiopoietin1 induced PI3 Kinase/AKT signaling in endothelial cells

Harprit Singh - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Interleukin

Phosphodiesterase 1 (PDE1) inhibition enhances prostacyclin mediated signalling in pulmonary artery smooth muscle cells through a novel selective pde1c:prostacyclin receptor interaction

Zaher Al Bakour - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Prostacyclin

Stabilisation of suppressor of cytokine signalling 3 (SOCS3) to inhibit human saphenous vein smooth muscle cell proliferation and vascular stenosis

Tim Palmer - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Trypsin

TRPV4 is a phospholipase C coupled receptor when mitochondria are depolarised in intact endothelial cells

Xun Zhang - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

GSK1016790A

mRNA expression profiling of dual specificity phosphatases (DUSPS) in the hypertensive heart

Zoe Haines - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

Angiotensin II

Investigating the role of salt-inducible kinase 2 (SIK2) in heart

Cecilia Facchi - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model

Jarka Naser - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

c-REL drives atherosclerosis at sites of disturbed blood flow

Blanca Tardajos Ayllón - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Radiotranscriptomic analysis of perivascular adipose tissue quantifies vascular inflammation in covid-19 from routine CT angiograms: Stratification of “new UK variant” Infection and prediction of in-hospital outcomes

Christos P Kotanidis - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Coronavirus disease

N/A

Impaired myocardial energetics as the basis for exercise-induced pulmonary congestion in heart failure with preserved ejection fraction

Matthew K Burrage - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Heart failure with preserved ejection fraction

Adenosine-5'-triphosphate

Female speaker representation at national cardiology conferences

Rebecca Dobson - British Cardiovascular Society (BCS) , 2021

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Risk Stratification Guided by the Index of Microcirculatory Resistance and Left Ventricular End-Diastolic Pressure During Primary Percutaneous Coronary Intervention

Annette Maznyczka - Transcatheter Cardiovascular Therapeutics (TCT) , 2020

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Myocardial infarction

alteplase

Implications of Impaired Coronary Flow on the Effects of Intracoronary Alteplase During Primary Percutaneous Coronary Intervention

Annette Maznyczka - Transcatheter Cardiovascular Therapeutics (TCT) , 2020

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Myocardial infarction

alteplase

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