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45280 Abstracts

Breaking the limitations of one-dimensional isometric assays: a novel technique for generating cardiac work-loops on adult cardiomyocytes to enhance our understanding of heart failure and myocardial recovery

Patrick Tran - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Congestive heart failure

N/A

Changes in myocyte architecture, contractile function and energetics in patients with heart failure before and after ventricular assist device implantation as a sign of myocardial recovery: a systematic review and meta-analysis

Patrick Tran - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

N/A

Ultra-highly flexible, accurate, high throughput platform for personalised drug screening studies.

Rob Krams - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

A novel physics-based artificial intelligence technique rapidly reconstructs the 3D velocity, shear stress and pressure fields in coronary arteries.

Rob Krams - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Ultra-highly flexible, accurate, high throughput platform for knock-in studies.

Rob Krams - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Oxidation of protein kinase a regulatory subunit PKARIα alpha regulates vasodilation and blood pressure lowering

Olena Rudyk - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Catecholamine

Loss of full-length MYLK3 causes dilated cardiomyopathy via a MYL2-independent mechanism.

Jack Williams - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Dilated cardiomyopathy

N/A

Micro-rnas as biomarkers for fibrosis in asymptomatic aortic stenosis

Jemima Osekafore Adewuyi - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Aortic stenosis

N/A

Macrophage-specific deletion of neuropilin-2 inhibits inflammatory signalling and attenuates atherosclerotic plaque development in apoe-deficient mice

Caroline Pellet-Many - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

N/A

Metabolic heterogeneity between endothelial cells from different vascular beds

Corey McAleese - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Evidence for a novel smooth muscle cell transdifferentiation pathway that underpins formation of the fibrous cap in atherosclerosis

James Taylor - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Coronary Artery Disease

N/A

The adipocyte calcium-sensing receptor is important is female visceral and perivascular adipose function

Laura Dowsett - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Aberrant mechano-transduction in iPSC-derived vascular smooth muscle cells modelling aortic aneurysm in marfan syndrome

Deeti Shetty - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Marfan syndrome

N/A

Restoring dilation in human internal mammary arteries from hypertensive coronary artery bypass graft patients, using liposome-delivered cyp1b1 inhibitor, tetramethoxystilbene.

Azziza Zaabalawi - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertension

Nitroprusside sodium

Endothelial TWIST1 enhances features of atherosclerotic plaque stability

Blanca Tardajos-Ayllon - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Coronary Artery Disease

Tamoxifen

Pim kinase: a novel regulator of thromboxane A2 receptor signalling and platelet function

Sophie Nock - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

AZD-1208

Ketohexokinase inhibition protects against sucrose-induced endothelial dysfunction and insulin resistance

Hema Viswambharan - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Vasodilation dysfunction

N/A

The senescence-associated secretory phenotype as a biomarker for age-related myocardial remodelling and cardiovascular disease

Laura Booth - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Congestive heart failure

Doxorubicin

A scaffold for heart repair: using human embryonic stem cell derived (HESC) epicardial extracellular matrix to enhance hesc-cardiomyocyte function

Jonathan Lee - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

snhg18 controls vascular smooth muscle cell phenotypic modulation and neointimal hyperplasia

Kaiyuan Niu - British Cardiovascular Society (BCS) , 2023

Therapeutic Area

Disease

Drug/Treatment

Angiology

Calcified vascular disease

Adenosine

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