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A rapid genetic diagnosis for >80% individuals with non-CAH Primary Adrenal Insufficiency is achievable by candidate gene sequencing combined with WES

Chris Smith - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Familial glucocorticoid deficiency

Glucocorticoid

Diagnostic accuracy of basal cortisol level to predict secondary adrenal insufficiency in patients with pituitary disease

Campbell Mathieson - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Addison's disease

Tetracosactide

Modified release hydrocortisone capsules (MRHC, Efmody) improve control of congenital adrenal hyperplasia (CAH) on a lower glucocorticoid dose than standard treatment

Aled Rees - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Congenital disorder

Congenital adrenal hyperplasia

Hydrocortisone

Improved biochemical control with modified-release hydrocortisone overturns the impaired fludrocortisone effect in salt-wasting CAH patients

Lea Tschaidse - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

N/A

Fludrocortisone

Fertility in congenital adrenal hyperplasia (CAH) patients on modified release hydrocortisone capsules (MRHC, Efmody)

Lea Tschaidse - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Congenital disorder

Congenital adrenal hyperplasia

Hydrocortisone

Macro-GH – a novel clinical entity causing a diagnostic challenge – a case report

Maria Stelmachowska-Banas - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

N/A

hGH

Pre-treatment GH levels and number of therapeutic interventions for acromegaly management are predictive of altered MRI bone shape and severity of arthropathy in acromegaly

Nikolaos Kyriakakis - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Acromegaly

N/A

Empagliflozin induces endocan expression and alleviates NAFLD through regulation of NF-κB pathway

Narjes Nasiri-Ansari - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Gastroenterology (GU)

Nonalcoholic fatty liver disease

BI-10773

How do people with type 2 diabetes compare with type 1 diabetes in their outcomes of diabetes-related ketoacidosis?

Amy Birchenough - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Type 1 diabetes mellitus

N/A

Osilodrostat therapy improves physical manifestations of hypercortisolism in patients with cushing’s disease: findings from the phase III LINC 3 study

Rosario Pivonello - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Cushing's syndrome

LCI699

Primary bile acids differentially regulate differentiation of human abdominal and gluteal pre-adipocytes

Rugivan Sabaratnam - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Type 2 diabetes mellitus

Cholbam

Differences in prevalence of, and precipitating factors for, diabetes related ketoacidosis in type 1 and type 2 diabetes mellitus

Dengyi Zhou - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Type 2 diabetes mellitus

N/A

Association of Early Adulthood Hyperandrogenemia With Hypertension and Cardiovascular Events in Women

Katri Tuorila - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Myocardial infarction

Androgen Tear

Mild autonomous cortisol secretion in patients with adrenal incidentalomas and raised cardiovascular risk

Rebecca Sagar - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Type 2 diabetes mellitus

Dexamethasone

Prevention of glucocorticoid-induced adipose dysfunction and hepatic lipid deposition through cold acclimation in aged mice

Manuel Gado - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Obesity

Glucocorticoid

A rare ARMC5 mutation causing bilateral macronodular adrenal hyperplasia and Cushing’s syndrome

Janki Panicker - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Cushing's syndrome

Dexamethasone

Long-term cardiometabolic morbidity in young adults wWith classic 21-hydroxylase deficiency congenital adrenal hyperplasia

Beatrice Righi - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Congenital disorder

Congenital adrenal hyperplasia

N/A

Waking salivary cortisone as screening test for adrenal insufficiency

Miguel Debono - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Addison's disease

Glucocorticoid

SIMBA for Students: teaching preclinical medical and pharmacy students endocrinology through online simulation - a pilot study

Isabel Allison - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

N/A

Bilateral adrenal haemorrhages secondary to Rivaroxaban on a background of p-ANCA vasculitis

Mohammad Farhan Malik - European Congress of Endocrinology (ECE) , 2022

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Deep vein thrombosis

Hydrocortisone

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