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45280 Abstracts

Stiffness of subchondral bone of grafts and defect site in osteochondral repair influences stability of repair

M.E. Casper-Taylor - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Osteoarthritic subchondral bone marrow histology. Lessons from changes in alkaptonuria

A. Boyde - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Alkaptonuria

N/A

The primary cilia protein IFT88, exerts a profound and evolving influence in the post-natal joint, through joint maturation, adult life and in disease

C.R. Coveney - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

BSE-SEM studies of articular cartilage and subchondral bone in naturally occurring post-traumatic equine carpal osteoarthritis

A. Boyde - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

Hysept

OMIC investigation of the chondrocyte response to varying mechanical load: assessment of impact stress

S.M. Higgins - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

streptomycin

Evidence for alternative polyadenylation of the ADAMTS5 mRNA creating a heterogenous pool of transcripts that differ in their response to post-transcriptional cues

B.T. McDermott - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Quasi-static loading reveals interaction between mechanics and mtor and NF-ĸB pathways in the control of endochondral ossification in mouse metatarsals

S. Caetano-Silva - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

amphotericin b cholesteryl sulfate complex Intravenous

Extracellular chemical profiling by LC-QTOF-MS identifies novel bone resorption markers for monitoring progression of osteoarthropathy in the rare disease alkaptonuria

B.P. Norman - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Alkaptonuria

N/A

APPA, a potential new therapy for osteoarthritis, inhibits neutrophil pro-inflammatory functions without impairing host defence

A. Cross - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Differential effects of exosomes derived from separate osteoarthritis synovial compartments: implications for erosive cartilage disease

S. Asghar - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Effects of nifedipine on the metabolism of mesenchymal stem cells and chondrocytes

I. Uzieliene Jr - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Tuberculosis

Nifedipine

Role for protein kinase R in bone cell signalling

S. Gilbert - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Alkaline phosphatase

The gate to controlling chondrogenic differentiation: transcriptional regulation by SOX9 in ATDC5 cells

M.M. Caron - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Physical activity, quality of life and sport-related concerns in relation to radiographic knee osteoarthritis and knee symptoms 32-37 years after anterior cruciate ligament injury

S.R. Filbay - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

N/A

Physical activity and health-related quality of life in former cricketers with persistent upper-limb or lower-limb joint pain

G.S. Bullock - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Estimating patient-specific mortality after joint replacement: algorithm development and validation using national audit datasets

J.M. Wilkinson - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Radiographic osteoarthritis and knee symptoms 32-37 years following acute anterior cruciate ligament injury

H. Gauffin - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Placebo effects of local (intra-articular) therapy in osteoarthritis – an individual patient data meta-analysis protocol

S.P. Yu - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

Hyaluronic acid

Cartilage imaging for experimental medicine studies: 6-month changes in morphology and composition can be detected by 3D cartilage surface mapping of knee magnetic resonance imaging data

J.W. MacKay - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

Methadone hydrochloride

The burden of osteoarthritis pain from patient’s perspective in the United States

J. Jackson - Osteoarthritis Research Society International (OARSI) , 2019

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

Epimorph

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