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45280 Abstracts

Connective tissue growth factor determines cartilage thickness and osteoarthritic risk by controlling activation of latent transforming growth factor beta in cartilage

X. Tang - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

The role of transient receptor potential cation channel trpc6 activity in cxcr2-mediated chondrocyte phenotypic stability

J. Sherwood - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Prediction of risk for radiographic hip osteoarthritis in subjects with early osteoarthritis of hip or knee

W.P. Gielis - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis 5

N/A

Development of quantitative in vivo imaging of articular cartilage degradation in murine osteoarthritis

P. Das Neves Borges - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

L-Tyrosine

Knee osteoarthritis and the risk of premature mortality in the community: an international individual patient level meta-analysis in 9889 subjects

K.M. Leyland - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Knee osteoarthritis

N/A

Novel translational discovery study of genes and SNPs associated with osteoarthritis pain

R.E. Miller - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Pain (neuropathic)

N/A

Investigating the systemic inflammatory status of a subgroup of osteoarthritis patients who display both altered cartilage DNA methylation and expression of inflammatory genes

E. Rogers - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Systemic inflammation

N/A

Persistent global inflammation caused by the loss of SIRT1 protects against experimental osteoarthritis

P. Sacitharan - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Identification of five novel osteoarthritis susceptibility loci through the UK biobank resourse of five novel osteoarthritis susceptibility loci through the UK biobank resourse

E. Zengini - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

National clinical audit data decodes the genetic architecture of developmental dysplasia of the hip

K. Hatzikotoulas - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

The effect of age and puberty on proximal femur shape

M. Frysz - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Novel models of late onset, progressive osteoarthritis caused by point mutations in the two alpha chains of collagen type I

A.M. Blease - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Effect of bisphosphonate use on trajectories of MRI-based three-dimensional bone shape of the knee over four years

T. Neogi - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Associations between metabolic syndrome and hand osteoarthritis: data from the Framingham study

M.S. Strand - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Rheumatoid arthritis

N/A

Whole genome sequencing finds rare high-risk genotypes for hip osteoarthritis in the COMP and CHADL genes

T. Ingvarsson - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

Chondroprotection by urocortin involves blockade of a mechanosensitive piezo1 ion channel: novel, exploitable pathways for the treatment and prevention of osteoarthritis?

K.M. Lawrence - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

forskolin

Baseline knee shape discriminates cases of incident knee radiographic oa from controls: a case-control study using novel methodology from the Johnston county osteoarthritis project

A.E. Nelson - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

Musculoskeletal

Osteoarthritis

N/A

The effect of donor age on engineered tendon tissue derived from tenocytes and mesenchymal stem cells

A.J. Turlo - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

anti-thymocyte equine

The effect of small molecule anti-inflammatory inhibitors on cartilage degradation is dependent on specific cytokine pathways

C.S. Thudium - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Tasocitinib

Associations between BMI across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort

S. Muthuri - Osteoarthritis Research Society International (OARSI) , 2017

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

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