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45280 Abstracts

First In Human Liver Biopsy Study Following Gene Therapy for Hemophilia A

S. Fong - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Blood/haematological Diseases

Hemophilia

N/A

First-in-Human Gene Therapy Study of AAVhu37 Capsid Vector Technology in Severe Hemophilia A: Safety and FVIII Activity Results

S.W. Pipe - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Blood/haematological Diseases

Hemophilia

FVIII

First-in-Human Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of ONO-7684, an Oral Small Molecule Factor XIa Inhibitor in Healthy Subjects

D. Beale - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Fixed Dose Rivaroxaban Can Be Prescribed in Extremes of Bodyweight, Results of a Population Pharmacokinetic Analysis

V. Speed - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Nephrology

Renal insufficiency

rivaroxaban

Force-induced Unfolding of the Autoinhibitory Module Activates VWF

N. Arce - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Fostamatinib as Second-Line Therapy for ITP and in Earlier Stage ITP Patients

W. Ghanima - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Fostamatinib

FVIII Assay and APTT Results on Obizur in-vitro Spiked Plasma Samples: Analysis from the First UK National External Quality Assurance Scheme for Blood Coagulation (UK NEQAS BC) Obizur Exercise

A. Lowe - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Susoctocog alfa

FXIII Catalyses Histone-Fibrin Crosslinking to Inhibit Fibrinolysis

M. Locke - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Generation and Isolation of Extracellular Vesicles from Endothelial and Smooth Muscle Cells Grown out of Human Blood

P. Ferreira - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Genetic Analysis for Investigation of Heritable Bleeding and Thrombotic Disorders – Variable Interpretation of Data Identified by the UK National External Quality Assessment Scheme (UK NEQAS) Blood Coagulation Programme

I. Jennings - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Genetic Dissection of Structural Variants in the Largest Cohort of Patients with Antithrombin Deficiency and Characterisation of the First Complex Structural Variant in SERPINC1 by Long-read Whole Genome Sequencing

B. de la Morena-Barrio - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Genetic Study of von Willebrand Factor Variants in Congenital Thrombotic Thrombocytopenic Purpura Patients

C. Lupo - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Thrombotic thrombocytopenic purpura

N/A

Gynaecological Outcomes in Women with Inherited Platelet Function Disorders: Preliminary Data from the ISTH REDCap Registry

D. Obeng-Tuudah - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Gynaecological Problems, Management and Outcomes in Women with Moderate and Severe von Willebrand Disease (VWD)

O. Turan - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Pulmonary/Respiratory Diseases

Hemophilia

N/A

Haemostatic Changes in Patients Undergoing Renal Transplantation

R. Kohli - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

FVIII

Haemostatic Markers in Cardiopulmonary Bypass Surgery

A. Ranger - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

Protamine Sulfate

Hemlibra Treatment in Pediatric Hemophilia A Patients – Real World Data of Safety and Uptake in the PedNet Cohorts

G. Kenet - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Blood/haematological Diseases

Hemophilia

N/A

Hip Bleeds in Boys with Mild Haemophilia A: A Single Centre Experience

D. Gosrani - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

Blood/haematological Diseases

Hemophilia

N/A

How Does the Availability of Thromboelastography Influence Clinical Reasoning in a Paediatric Intensive Care Unit? A Narrative View

A. Knott - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

Identification and Functional Study of a New Germline Variant in Mecom Gene

N. Papa - Society of Thrombosis and Hemostasis Research (GTH/ISTH) , 2020

Therapeutic Area

Disease

Drug/Treatment

N/A

N/A

N/A

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