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Comparative Impact of Isolated Systolic Hypertension vs Systolic-Diastolic Hypertension on Incident Heart Failure and All-Cause Mortality in Community-Dwelling Older Adults

Ross Fletcher - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertension

N/A

Relationship of PCSK9 With Measures of Vascular Disease and Global Risk in 1574 Individuals Enrolled in the FATE (Fireman And Their Endothelium) Study

Eva M Lonn - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Coronary Artery Disease

Nitroglycerin

Major Adverse Cardiac Events After Non-cardiac Surgery Following Previous Percutaneous Coronary Intervention With Stent Implantation

Summer Syed - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Blood/haematological Diseases

Venous thrombosis

Clopidogrel bisulfate

Spatial Distribution of the Metabolically Active Pulmonary Circulation in Humans

Francois Harel - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

N/A

Adrenomedullin

Annulus Preservation Strategy Improves Late Outcomes in Tetralogy of Fallot: An Anatomical Equivalency Study

Tae-Jin Yun - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Tetralogy of fallot

N/A

Left Ventricular Assist Device Normalizes Multiple Pathogenic Pathways in Both the Left and Right Ventricle in Patients With Dilated Cardiomyopathy

Rene R Packard - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Dilated cardiomyopathy

N/A

Angiotensin Converting Enzyme 2 Deficiency Results in Cardiac Insulin Resistance in Response to High-Fat Diet

Jun Mori - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Diastolic dysfunction

Angiotensin II

Loss of Gelsolin Attenuates Pressure Overload Induced Heart Failure: Novel Role of Gelsolin in Cardiac Biomechanical Stress Induced Cytoskeletal Remodeling

Pavel Zhabyeyev - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Heart failure with reduced ejection fraction

N/A

Right Ventricular Dysfunction is Common in Patients With Breast Cancer Experiencing Cardiotoxicity During Adjuvant Trastuzumab Therapy

Frederic Poulin - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Oncology (ONC)

Right ventricular dysfunction

Trastuzumab

Discrepancy Between Originally Assigned and Adjudicated Causes of Out-of-Hospital-Cardiac-Arrest of No Obvious Cause in Young Patients

Katherine S Allan - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Central Nervous System (CNS)

Cardiac arrest

N/A

Lentil-Based Diets Reduce Vascular Remodeling Through a p38 Mitogen-Activated Protein Kinase Dependant Mechanism in the Spontaneously Hypertensive Rat

Peter Zahradka - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Arterial stiffness

N/A

Salt Taste Detection and Recognition Thresholds - Reliability of a Rapid Sensory Analysis Method

Maria-Cecilia Gallani - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Endocrine/metabolic Diseases (ME)

Hypertension

N/A

A Mir-208-mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension

Gopinath Sutendra - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Right ventricular failure

Monocrotaline

Clinical and Hemodynamic Factors Influence the Risk of Pulmonary Hypertension in Patients Undergoing Transcatheter Aortic Valve Replacement: Insights from the PARTNER I Trial and Registry

Alan Zajarias - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Pulmonary arterial hypertension

N/A

The Sirt1 Activator, SRT1720, Attenuates Cardiac Hypertrophy and Fibrosis in a Rodent Pressure Overload Model

Robert A Civitarese - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Hypertrophic cardiomyopathy

SRT1720

Hyperoxia Reduces Oxygen Consumption in Children With Pulmonary Hypertension

Prashant Bobhate - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Infectious Diseases (ID)

Pulmonary arterial hypertension

INO

Variation in Treatment and Outcomes in ACS: Insights from the Alberta Contemporary Acute Coronary Syndrome Patients Invasive Treatment Strategy (COAPT) Study

Padma Kaul - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Cardiovascular (CVS)

Acute Coronary Syndromes

N/A

Genetic Variants Primarily Associated With Inflammatory Bowel Disease Do Not Associate With Coronary Artery Disease

Deutsches Herzzentrum Munchen - American Heart Association (AHA) , 2014

Therapeutic Area

Disease

Drug/Treatment

Autoimmune (AI)

Inflammatory bowel disease

N/A

The Relationship of Parent Well-Being, Family Management, and Service Utilization in Families of Children With Hypoplastic Left Heart Syndrome From the Perspective of Mothers and Fathers

Tamara Dorfman - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Hypoplastic left heart syndrome

N/A

Novel Linkage Between Metabolic Sensor Mechanistic Target of Rapamycin (mTOR) and Canonical NF-kB Signaling Pathway Preserves Mitochondrial Integrity in Ventricular Myocytes During Hypoxia

Rimpy Dhingra - American Heart Association (AHA) , 2013

Therapeutic Area

Disease

Drug/Treatment

Genetic Disorder

Mitochondrial Injury

Rapacan

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