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: Safety, Efficiency and Long-Term Follow-up of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Researchers

Presenter

  • Claire Roddie

Principal Investigators

  • Maeve A O'Reilly

  • Marina Mitsikakou

  • Eftychia Charalambous

  • Louisa Green

  • Mhairi Vaughan

  • Giulia Agliardi

  • John Garcia

  • Evie Lewin

  • Mark W. Lowdell

  • Maria A V Marzolini

  • Leigh Wood

  • Helen Holmes

  • Yenting Ngai

  • Bilyana Popova

  • William Wilson

  • Sangeetha Kunaseelan

  • Victoria Spanswick

  • Helen Lowe

  • Leah Ensell

  • John A. Hartley

  • Simon Morley

  • David C. Linch

  • Adrian Bloor

  • David A. Irvine

  • Martin Pule

  • Karl S Peggs

Medical Centers

  • UCL Cancer Institute, London, United Kingdom

  • UCL Cancer Trials Centre, London, United Kingdom

  • University College London Cancer Institute, London, United Kingdom

  • Queen Elizabeth University Hospital, Glasgow, Scotland, GBR

  • University College London Hospital NHS Foundation Trust, London, United Kingdom

  • Cancer Institute, University College London, London, GBR

  • CRUK UCL Cancer Trials Centre, University College London, London, United Kingdom

  • University College London Hospital, London, United Kingdom

  • Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

  • UCL ECMC GCLP Laboratory, University College London, London, United Kingdom

  • Haematology, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • B cell lymphomas

  • Diffuse large B-cell lymphoma

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Cluster of Differentiation 19

  • Coxsackie Virus And Adenovirus Receptor

  • Twist-related protein 1

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Pembrolizumab

  • fludarabine tablet

Outcome

  • N/A

Study Design

  • Safety

  • Cohort

  • Feasibility

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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