// App-Quantinova.ai

: Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial

Researchers

Presenter

  • Swati Naik

Principal Investigators

  • Amanda Lipsitt

  • Timothy Lockey

  • Jennyfer Bran

  • Jeffrey E. Rubnitz

  • Jeffery Klco

  • Barry Shulkin

  • Sagar L. Patil

  • Sarah Schell

  • Jeoungeun John Park

  • Janice Riberdy

  • Na Shang

  • Jaquelyn T. Zoine

  • Jennifer Wallace

  • Elaine Harstead

  • Catherine Willis

  • Jean-Yves Metais

  • Deanna M. Langfitt

  • Sheng Zhou

  • Salem M. Akel

  • Michael M. Meagher

  • Brandon M. Triplett

  • Stephen Gottschalk

  • Mireya Paulina Velasquez

Medical Centers

  • Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN

  • St. Jude Children's Research Hospital, Memphis, TN

  • Department of Diagnostic Imaging, St. Jude Children's Research Hospital, University of Tennessee Health Science Center, Memphis, TN

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Therapeutics Production and Quality, St. Jude Children's Research Hospital, Memphis, TN

  • Experimental Cellular Therapeutics Laboratory, St. Jude Children's Research Hospital, Memphis, TN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Autoimmune (AI)

Disease

  • Acute lymphoblastic leukemia

  • Cytokine release syndrome

Biomarkers

  • B-lymphocyte antigen CD20

  • Cluster of Differentiation 4

  • Cytokine

  • Hematocrit

  • Interleukin 6

  • Interleukin-15

  • Twist-related protein 1

  • Type 1 T helper

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • fludarabine tablet

  • dasatinib

Outcome

  • N/A

Study Design

  • Safety

  • Feasibility

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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