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: Circulating RAS/RAF and DNA-Repair Gene Mutations Associates with High-Risk/Treatment Resistance in Primary Refractory Multiple Myeloma

Researchers

Presenter

  • Sridurga Mithraprabhu

Principal Investigators

  • John Reynolds

  • Rose Turner

  • Hang Quach

  • Noemi Horvath

  • Ian H Kerridge

  • Flora Yuen

  • Tiffany Khong

  • Brian G.M. Durie

  • Andrew Spencer

Medical Centers

  • Department of Haematology, The Alfred Hospital and Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia

  • Clinical Haematology Service, St. Vincent's Hospital, Melbourne, Australia

  • Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Outpatient Cancer Center, Los Angeles, CA

  • Clinical Hematology, Alfred Health, Melbourne, Australia

  • Department of Haematology, Royal Adelaide Hospital, Adelaide, Australia

  • Australian Center for Blood Diseases, Myeloma Research Group, Alfred Hospital, Monash University, Melbourne, Australia

  • The Alfred Hospital and Monash University, Melbourne, Australia

  • Myeloma Research Group, Australian Centre for Blood Diseases, Monash University, Melbourne, Australia

  • Alfred Hospital, Melbourne, Australia

  • Royal North Shore Hospital, Sydney, Australia

Locations

  • Australia

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Multiple Myeloma

  • Lymphomas

Biomarkers

  • Circulating DNA

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • carfilzomib Intravenous

  • Thalidomide

Outcome

  • N/A

Study Design

  • Single Arm

  • Multinational

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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