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: Final Results of Phase I/II Trial of Mitoxantrone in Combination with Clofarabine (MITCL) in Children with Relapsed/Refractory Acute Leukemia

Researchers

Presenter

  • Jessica C Hochberg

Principal Investigators

  • Javier Oesterheld

  • Aliza Gardenswartz

  • Liana Klejmont

  • Jaclyn Basso

  • Elizabeth Mintzer

  • Lauren Harrison

  • Michael J Borowitz

  • Michael R. Loken

  • Mitchell S Cairo

Medical Centers

  • Department of Pediatrics, New York Medical College, Hawthorne, NY

  • New York Medical College, Departments of Pediatrics, Medicine, Pathology, Microbiology and Immunology, and Cell Biology and Anatomy, Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY

  • New York Medical College, Valhalla, NY

  • Departments of Pathology and Oncology, Johns Hopkins Hospital, Baltimore, MD

  • Levine Children's Hosp., Charlotte, NC

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Acute Leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Mitoxantrone

  • Clofarabine

  • Cytarabine liposomal

Outcome

  • N/A

Study Design

  • Efficacy

  • Safety

  • Prospective

  • Dose Escalation

Phase

  • I/II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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