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: Fractionated Inotuzumab Ozogamicin Combined with Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL): Results of the EWALL-INO Study

Researchers

Presenter

  • Patrice Chevallier

Principal Investigators

  • Rathana Kim

  • Marc Delord

  • Michael Doubek

  • Francoise Huguet

  • Aurelie Cabannes-Hamy

  • Ulla Wartiovaara-Kautto

  • Colombe Saillard

  • Emmanuel Raffoux

  • Thomas Cluzeau

  • Stephane Lepretre

  • Marie Balsat

  • Anna Berceanu

  • Nicolas Boissel

  • Claude Gardin

  • Emmanuelle Clappier

  • Herve Dombret

  • Philippe Rousselot

Medical Centers

  • Hematology Department, Centre Hospitalier de Versailles, LE CHESNAY CEDEX, France

  • Direction à la recherche clinique et à l'innovation, Centre hospitalier de Versailles, Le Chesnay, France

  • Hematology Laboratory and INSERM U, Université de Paris, Saint-Louis Hospital, Paris, France

  • Institut Paoli Calmettes, Marseille, France

  • Hematology Adolescent and Young Adult Unit, Saint-Louis Hospital, Paris, France

  • Service d'Hematologie, CHU de Toulouse- Institut Universitaire de Cancérologie de Toulouse Oncopole, Toulouse, France

  • Hematology Unit, Versailles Hospital, Le Chesnay, France

  • Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France

  • Hematology Department, Nantes University Hospital, Nantes, France

  • Clinical hematology service, Hospices Civils de Lyon, Lyon, France

  • Department of Hematology, Université Côte d'Azur, Centre Hospitalier Universitaire, Nice, France

  • Department of Hematology, University of Helsinki, Helsinki, Finland

  • Clinical Hematology, Besançon University Hospital, Besançon, France

  • Centre Henri Becquerel, Rouen, Rouen, FRA

  • Hopital Saint-Louis, Assistance Publique - Hopitaux De Paris (AP-HP), Paris, FRA

  • Bordeaux University Hospital, Pessac, FRA

  • Hematology Department, Avicenne Hospital, Bobigny, France

  • Hematology laboratory, Assistance Publique Des Hopitaux De Paris (AP-HP) - Universite Paris Descartes -, Paris, France

  • Department of Internal Medicine - Hematology and Oncology, University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic

Locations

  • France

  • Finland

  • Czech Republic

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • N/A

Drug/Treatment

  • Inotuzumab ozogamicin

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Methotrexate

  • Vincristine

  • ara-c

  • Etoposide phosphate

  • 6-mercaptopurine

Outcome

  • N/A

Study Design

  • Single Arm

  • Prospective

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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