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: Coagulation Factor XII Is Activated Via Noncanonical Binding to Platelet Integrin αIIbβ3

Researchers

Presenter

  • Sharjeel Chaudhry

Principal Investigators

  • Randall Burton

  • Matthew Serrata

  • Louis Feingold

  • Lindsay Tomczak

  • Lindsay Collier

  • Dylan Laprise

  • Keiichi Enjyoji

  • Virendar Kaushik

  • Dylan Bertovich

  • Alex Burgin

  • Pavan K. Bendapudi

Medical Centers

  • Division of Hematology and Blood Transfusion Service, Massachusetts General Hospital, Cambridge, MA

  • Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Boston, MA

  • Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, MA

  • Harvard Medical School, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Glanzmann thrombasthenia

  • Venous thrombosis

Biomarkers

  • Integrin subunit beta 3

Drug/Treatment

  • eptifibatide

  • Fibrinogen (IV)

  • PAC-1

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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