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: Effect of the Neddylation Inhibitor Pevonedistat on Normal Hematopoietic Stem Cell Subsets and Immune Cell Composition

Researchers

Presenter

  • Fatemeh Majidi

Principal Investigators

  • Oumaima Stambouli

  • Ron-Patrick Cadeddu

  • Simon Kai Brille

  • Jasmin Ewert

  • Ulrich Germing

  • Robert Zeiser

  • Bernd Giebel

  • Norbert Gattermann

Medical Centers

  • Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg im Breisgau, Germany

  • Dept. of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

  • Institute for Transfusion Medicine, University Hospital Essen, Essen, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • cMYC

  • Cluster of Differentiation 4

  • Cluster of Differentiation 34

  • Epidermal growth factor receptor

  • Cluster of differentiation 8A

  • Intercellular adhesion molecule 1

  • Mesenchymal stem cells

Drug/Treatment

  • Pevonedistat

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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