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TMIC-31 : ADI-PEG20 RESTORES IMMUNITY IN THE TUMOR MICROENVIRONMENT AND ERADICATES GBM TUMORS IN MICE WHEN COMBINED WITH RADIATION

Researchers

Presenter

  • Jake Symington

Principal Investigators

  • Richard Perryman

  • Sophie Morse

  • Kevin O'Neill

  • Elizabeth Want

  • Nelofer Syed

Medical Centers

  • Imperial College NHS Trust, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Oncology (ONC)

Disease

  • Glioblastoma

  • Cerebral metastases

Biomarkers

  • Cluster of Differentiation 11c

  • Cluster of Differentiation 4

  • Programmed cell death protein 1

  • Programmed death-ligand 1

Drug/Treatment

  • ADI-PEG20

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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