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TCT CONNECT-417 : Impact of Renal Denervation on Plasma Renin Activity and Relationship of Baseline Plasma Renin Activity to Blood Pressure Lowering Response to Renal Denervation in the SPYRAL HTN-OFF MED Pivotal trial

Researchers

Presenter

  • Felix Mahfoud

Principal Investigators

  • Raymond Townsend

  • David Kandzari

  • Kazuomi Kario

  • Roland Schmieder

  • Konstantinos Tsioufis

  • Michael Bohm

  • Stuart Pocock

  • Sidney Cohen

  • Martin Fahy

  • Michael Weber

Medical Centers

  • Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

  • Jichi Medical University School of Medicine, Tochigi, JAPAN

  • Saarland University Medical Center, Homburg, GERMANY

  • First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Athens, Greece

  • SUNY Downstate Medical Center, New York, New York, USA

  • Universitatskliniken des Saarlandes, Klinik fur Innere Medizin III, Homburg/saar, Germany

  • Univ. Hospital Erlangen, Erlangen, Germany

  • Medtronic, Pleasanton, California

  • London School of Hygiene and Tropical Medicine, London, United Kingdom

  • Medtronic, Santa Rosa, California

  • Piedmont Heart Institute, Atlanta, GA

Locations

  • United States

  • Germany

  • Japan

  • United Kingdom

  • Greece

  • Georgia

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Cartilage oligomeric matrix protein

  • Plasma Renin Activity

  • Renin

Drug/Treatment

  • Angiotensin II

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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