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1373 : STC-15, an oral small molecule inhibitor of the RNA methyltransferase METTL3, inhibits tumour growth through activation of anti-cancer immune responses and synergises with immune checkpoint blockade

Researchers

Presenter

  • Yaara Ofir -Rosenfeld

Principal Investigators

  • Oliver Rausch

  • Jerry McMahon

  • Lina Vasiliauskaite

  • Claire Saunders

  • Alexandra Sapetschnig

  • Georgia Tsagkogeorga

  • Mark Albertella

  • Marie Carkill

  • Jezrom Self-Fordham

  • Josefin-Beate Holz

Medical Centers

  • F-star Therapeutics Ltd, Cambridge, UK

  • Charles River Laboratories, Portishead, UK

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Oncology (ONC)

Disease

  • Gynaecological cancer

Biomarkers

  • Peripheral blood mononuclear cell

  • Cluster of differentiation 8A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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