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1324 : Inhibition of acid sensing by GPR65 normalises gene expression in macrophages, increases immune cell infiltration in tumors, and restrains subcutaneous MC38 growth in mice

Researchers

Presenter

  • Alastair Corbin

Principal Investigators

  • Stuart Hughes

  • Mussa Quareshy

  • Tobias Bopp

  • Barbara Cipriani

  • David Miller

  • Alan Naylor

  • Gavin Milne

  • Darryl Turner

  • Barbara Young

  • Anastasia Nika

  • Preeti Singh

  • Rupert Satchell

  • Sourav Sarkar

  • Gavin Knox

  • Toszka Bohn

  • Tom McCarthy

Medical Centers

  • Malvern Panalytical, Edinburgh, UK

  • University Medical Center Mainz, Mainz, Germany

Locations

  • United Kingdom

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • G Protein-Coupled Receptor 65

  • Stromal interaction molecule 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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