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777 : Initial clinical characterization of novel proximal biomarkers for NX-1607, a first-in-class oral CBL-B inhibitor, in patients with advanced malignancies

Researchers

Presenter

  • sarah whelan

Principal Investigators

  • Christopher Karim

  • Jordan Ye

  • Timothy Ingallinera

  • Ganesh Cherala

  • Katherine Jameson

  • Anja Williams

  • Adam Sharp

  • Matthew Krebs

  • Simon Pacey

  • Sarah Blagden

  • Ruth Plummer

  • Daniel Hochhauser

  • Jeff Evans

  • Johann de Bono

  • Janine Powers

Medical Centers

  • CR-UK Beatson Institute, Glasgow, UK

  • Royal Marsden NHS Foundation Trust, London, UK

  • Newcastle University Centre for Cancer, Newcastle upon Tyne, United Kingdom

  • Sarah Cannon Research Institute UK, London, UK

  • University of Cambridge, Cambridge, UK

  • University of Oxford, Oxford, Germany

  • University College Hospital, London,

  • The Christie NHS Foundation TRUST, Manchester, United Kingdom

  • The Institute of Cancer Research, London, UK

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Pharmacodynamics

Phase

  • I

Study Id's

  • NCT05107674

Sponsors

  • N/A

Result

  • Final

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