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P142 : Cytomegalovirus seropositivity is associated with an increased frequency of highly differentiated T effector memory cells re-expressing CD45RA (Temra) and persistent disease refractory to anti-TNF therapy in rheumatoid arthritis

Researchers

Presenter

  • Su-Ann Yeoh

Principal Investigators

  • James Kimpton

  • Muhammad Shipa

  • Ellie Hawkins

  • Arne Akbar

  • Michael Ehrenstein

Medical Centers

  • Academic Neonatology, University College London, London, United Kingdom

  • Experimental and Translational Medicine, University College London, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

  • Autoimmune (AI)

Disease

  • Rheumatoid arthritis

  • Cytomegalovirus infection

  • Inflammatory Arthritis

Biomarkers

  • Peripheral blood mononuclear cell

  • Protein Tyrosine Phosphatase, Receptor Type C

  • Immunoglobulin G

Drug/Treatment

  • Abatacept

Outcome

  • N/A

Study Design

  • Cross-Sectional

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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