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P130 : Transcriptomic analysis of synovitis identifies inhibition of CXCL1 as a mechanism contributing to resolution of inflammatory arthritis under IL-27 control

Researchers

Presenter

  • Isabel Burridge

Principal Investigators

  • Simon Eastham

  • David G Hill

  • Robert Andrews

  • Barbara Szomolay

  • Nigel Williams

  • Simon A Jones

  • Gareth W Jones

Medical Centers

  • Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

  • Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Inflammatory Arthritis

Biomarkers

  • Cluster of Differentiation 4

  • Chemokine (C-X-C motif) ligand 1

  • Interleukin 27

Drug/Treatment

  • Interferon Gamma

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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