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: Efficacy and safety of erdafitinib in adults with cholangiocarcinoma (CCA) with prespecified fibroblast growth factor receptor alterations (FGFRalt) in the phase 2 open-label, single-arm RAGNAR trial: Expansion cohort results.

Researchers

Presenter

  • Shubham Pant

Principal Investigators

  • Gopa Iyer

  • Toshihiko Doi

  • Shukui Qin

  • Josep Tabernero

  • Dirk Arnold

  • Martin Gutierrez

  • Hans Prenen

  • Gunnar Folprecht

  • Helen Winter

  • Rasha Cosman

  • Graziela Zibetti Dal Molin

  • Qi Xia

  • Saltanat Najmi

  • Constance Hammond

  • Shibu Thomas

  • Spyros Triantos

  • Hussein Sweiti

  • Yohann Loriot

Medical Centers

  • Jinling Hospital, Nanjing University School of Medicine, Nanjing, China

  • Vall d'Hebron Institute of Oncology, Barcelona, Spain

  • Universitair Ziekenhuis Antwerpen, Edegem, Belgium

  • Universitatsklinikum Carl Gustav Carus, Dresden, Germany

  • Janssen Research and Development, LLC, Spring House, PA

  • Asklepios Tumorzentrum Hamburg, Asklepios Klinik Altona, Hamburg, Germany

  • National Cancer Center Hospital, Tokyo, Japan

  • The Kinghorn Cancer Centre, St Vincent’s Hospital Sydney, The University of New South Wales, Sydney, NSW, Australia

  • Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil

  • The University of Texas MD Anderson Cancer Canter, Houston, TX

  • West German Cancer Center, University Hospital, Essen, Germany

  • Hackensack Meridian Health John Theurer Cancer Center, Hackensack, NJ

  • Gustave Roussy, Villejuif, France

  • University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, United Kingdom

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

Locations

  • United Kingdom

  • Australia

  • United States

  • Brazil

  • Belgium

  • China

  • Japan

  • Germany

  • Spain

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Advanced biliary tract carcinoma

Biomarkers

  • N/A

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • Open Label

  • Single Arm

  • Cohort

Phase

  • II

Study Id's

  • NCT04083976

Sponsors

  • N/A

Result

  • N/A

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