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: Association between artificial intelligence (AI) -assisted tumor AREG and EREG immunohistochemistry (IHC) and outcomes from anti-EGFR therapy during the routine management of metastatic colorectal cancer (mCRC): An observational cohort study.

Researchers

Presenter

  • Christopher Williams

Principal Investigators

  • Mike Shires

  • Henry Wood

  • Liping Zhang

  • Zuo Zhao

  • Isaac Bai

  • Dongyao Yan

  • Faranak Aghaei

  • Uday Kurkure

  • Chris Bacon

  • Sarah E Coupland

  • Simon Cross

  • D Chas Mangham

  • Abhik Mukherjee

  • Jenny F. Seligmann

  • Nicholas West

  • Shalini Singh

  • Kandavel Shanmugam

  • Philip Quirke

Medical Centers

  • Roche Diagnostics, Clinical Development and Medical Affairs, Oro Valley, AZ

  • Roche Diagnostics, Clinical Development and Medical Affairs, Oro Valley, AZ

  • University of Sheffield, Department of Psychology, Sheffield, United Kingdom

  • Roche Diagnostics, Santa Clara, CA

  • Leeds Cancer Centre, Leeds, United Kingdom

  • Newcastle University, Translational and Clinical Research Institute, Newcastle Upon Tyne, United Kingdom

  • Roche Diagnostics, Tucson, AZ

  • Adult Histopathology, Laboratory Medicine, Manchester University NHS Foundation Trust, Manchester, United Kingdom

  • Translational Medical Sciences, Division of Cancer and Stem Cells, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom

  • Division of Pathology and Data Analytics, University of Leeds, Leeds, United Kingdom

  • Roche Diagnostics, Oro Valley, AZ

  • University of Leeds, Leeds, United Kingdom

  • Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom

  • University of Liverpool, Liverpool, United Kingdom

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • Amphiregulin

Drug/Treatment

  • panitumumab

  • Erbitux

Outcome

  • N/A

Study Design

  • Observational

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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