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: Optimising longitudinal plasma-only circulating tumour DNA (ctDNA) for minimal residual disease (MRD) detection with combined genomic/methylation signals to predict recurrence in patients (pts) with resected stage I-III colorectal cancer (CRC) in the UK multicentre prospective study TRACC.

Researchers

Presenter

  • Susanna Slater

Principal Investigators

  • Maria Aresu

  • Ruwaida Begum

  • Hsiang-Chi Chen

  • Clare Peckitt

  • Retchel Lazaro-Alcausi

  • Paul Carter

  • Gayathri Anandappa

  • Shelize Khakoo

  • Graham Branagan

  • Nicol George

  • Muti Abulafi

  • Sarah Duff

  • Nicholas West

  • Leslie Bucheit

  • Thereasa A. Rich

  • Ian Chau

  • Naureen Starling

  • David Cunningham

Medical Centers

  • Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

  • Salisbury District Hospital, Rhuematology, Salisbury, United Kingdom

  • Royal Marsden Hospital, Surrey, United Kingdom

  • The Royal Marsden Hospital, London, United Kingdom

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • Guardant Health, Rewdwood City, CA

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • Neonatal Unit, Croydon University Hospital, London, United Kingdom

  • Guardant Health, Rewdwood City, CA

  • Epsom and St Helier University Hospitals, Surrey, United Kingdom

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

  • The Royal Marsden Hospital, London, Greater London, United Kingdom

  • Broomfield Hospital Mid and South Essex NHS Foundation Trust, Chelmsford, United Kingdom

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

Biomarkers

  • Circulating DNA

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Multicenteric

  • Prospective

Phase

  • NA

Study Id's

  • NCT04050345

Sponsors

  • N/A

Result

  • N/A

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