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: Resistance to thyroid hormone alpha: molecular, biochemical and physiological approach to diagnosis and therapy

Researchers

Presenter

  • Maura Agostini

Principal Investigators

  • Federica Marelli

  • Matina Prapa

  • Carla Moran

  • W. Edward Visser

  • Dave Brown

  • Ellen Thomas

  • Erik Schoenmakers

  • Beatriz Romartinez-Alonso

  • Rabea Scheuplein

  • Anna Tylki-Szymanska

  • Greta Lyons

  • Laura Watson

  • Odelia Rajanayagam

  • Edzard Schwedhelm

  • Michaela F. Hartmann

  • Stefan Wudy

  • Maiken Probst

  • Stephen MacDonald

  • William Thomas

  • Wiebke Arlt

  • Uwe Völker

  • Katharina M. Main

  • Ulla Feldt-Rasmussen

  • Mehul T. Dattani

  • Louise Koren Dahll

  • Korcan Demir

  • Cengiz Kara

  • Ozgur Kirbiyik

  • Jamala Mammadova

  • Atilla Çayır

  • Oguzhan Yarali

  • Franziska Phan-Hug

  • Rajesh Sakremath

  • Zainaba Mohamed

  • Marwan Shinawi

  • Harpreet Gill

  • Daniele pacaud

  • Renee Perrier

  • Gemma Poke

  • Wendy Hunter

  • Sofia Douzgou

  • Emma Wakeling

  • Alice Gardham

  • Derek Lim

  • Deborah Shears

  • Marie Freel

  • Jasna Omladic

  • Mojca Tansek

  • Karin Writzl

  • Sadaf Farooqi

  • Peter Kopp

  • John Schwabe

  • Luca Persani

  • Krishna Chatterjee

Medical Centers

  • Division of Pediatric Endocrinology, Dr Behcet Uz Childrens Hospitals Hospital, Izmir, Turkey

  • Institute of Metabolic Science, Clinical Biochemistry, Cambridge, United Kingdom

  • Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, United Kingdom

  • North West Thames Regional Genetics Service, Northwick Park Hospital, Harrow, United Kingdom

  • Henry Wellcome Laboratories of Structural Biology, University of Leicester, Institute of Structural and Chemical Biology, University of Leicester, Leicester, United Kingdom

  • Endocrine Dept, Endocrine, Ucd School of Medicine, Dublin, Ireland

  • Alberta Children’s Hospital, Department of Pediatrics, Calgary, Canada

  • The Children's Memorial Health Institute, Warsaw, Poland

  • Shrewsbury and Telford Hospital, United Kingdom

  • Steroid Research & Mass Spectrometry Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University, Gießen, Germany

  • Ondokuzmayis University, Medical School, Department of Paediatric Endocrinology and Diabetes, Samsun, Turkey

  • Department of Radiology, Addenbrooke's Hospital, Cambridge, United Kingdom

  • University of Milan, Irccs Istituto Auxologico Italiano, Ospedale San Luca, Milan, Italy

  • Institute of Metabolic Science, Cambridge, United Kingdom

  • Department of Medical Endocrinology, Section , Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, Rigshospitalet, Endocrinology, Copenhagen, Denmark

  • Tepecik Training and Research Hospital, University of Health Sciences, Genetic Diagnosis Center, Izmir, Turkey

  • University Medical Center, Institute of Genomic Medicine, Ljubjana, Slovenia

  • Genomics England, London, United Kingdom

  • Institute of Metabolism and Systems Research, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, , United Kingdom

  • Nelson Marlborough District Health Board, Department of Pediatrics, Nelson, New Zealand

  • Department of Growth and Reproduction, University of Copenhagen, Copenhagen, Denmark

  • Hormone Laboratory, Oslo University Hospital, Oslo, Norway

  • Oxford Centre for Respiratory Medicine, Oxford, United Kingdom.

  • Steroid Research & Mass Spectrometry Unit, Center of Child and Adolescent Medicine, Justus-Liebig-University, Gießen, Germany

  • Institut Fur Genetik und Funktionelle Genomforschung, Greifswald, Germany

  • Children’s Hospital, Department of Pediatrics, Ljubjana, Slovenia

  • University of Cambridge, Wellcome Trust–MRC Institute of Metabolic Science, Cambridge, United Kingdom

  • Berlin Institute of Health at Charité - Universitätsmedizin Berlin,Berlin,Germania

  • Institute for Clinical Pharmacology and Toxicology, Hamburg, Germany

  • Erzurum Regional Training and Research Hospital, Department of Internal Medicine, Erzurum, Turkey

  • Genetic Health Service Nz, Wellington Hospital, New Zealand

  • Great Ormond Street Hospital, Department of Clinical Genetics, London, United Kingdom

  • Department of Clinical Genetics, Addenbrooke’s Hospital, Cambridge, United Kingdom

  • Institute of Structural and Chemical Biology, Leicester, United Kingdom

  • Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt- University Greifswald, Greifswald, Germany

  • Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, United States

  • University of Cambridge, Wellcome Trust–MRC Institute of Metabolic Science, Cambridge, United Kingdom

  • St Mary’s Hospital, Department of Clinical Genetics, Manchester, United Kingdom

  • University Children's Hospital Basel, Division of Endocrinology, Diabetes, and Metabolism, Basel, Switzerland

  • Erasmus Medical Center, Academic Center for Thyroid Diseases, Department of Internal Medicine, Academic Center for Thyroid Diseases, Rotterdam, Netherlands

  • Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, UK

  • Erzurum Regional Training and Research Hospital, Clinics of Medical Genetics, Erzurum, Turkey

  • Ondokuz Mayis University, Department of Paediatric Endocrinology, Samsun, Turkey

  • Irccs Istituto Auxologico Italiano, Lab. of Endocrine and Metabolic Research, Lab of Endocrine and Metabolic Research, Cusano Milanino, Italy

  • Department of Pediatrics, Alberta Childrens Hospital, University of Calgary, Calgary, AB, Canada

  • Birmingham Women’s and Children’s Hospital, Department of Paediatric Endocrinology, Birmingham, United Kingdom

  • Queen Elizabeth University Hospital, Department of Endocrinology, Glasgow, United Kingdom

  • Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark

  • Birmingham Women’s and Children’s Hospital, Clinical Genetics Unit, Birmingham, United Kingdom

  • Great Ormond Street Hospital, London, United Kingdom

Locations

  • Ireland

  • Denmark

  • New Zealand

  • Italy

  • Slovenia

  • Turkey

  • Switzerland

  • Norway

  • Netherlands

  • Canada

  • United Kingdom

  • Germany

  • Poland

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Thyroid hormone resistance syndrome

  • Obesity

Biomarkers

  • Thyroid Hormone Receptor Alpha

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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