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: An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19

Researchers

Presenter

  • Bronwen Connolly

Principal Investigators

  • Chen Ji

  • Keith Couper

  • Ranjit Lall

  • J Kenneth Baillie

  • Judy M Bradley

  • Paul Dark

  • Chirag Dave

  • Anthony De Soyza

  • Anna V Dennis

  • Anne Devrell

  • Sara Fairbairn

  • Hakim Ghani

  • Ellen A Gorman

  • Christopher A Green

  • Nicholas Hart

  • Siew Wan Hee

  • Zoe Kimbley

  • Shyam Madathil

  • Nicola Mcgowan

  • Benjamin Messer

  • Jay Naisbitt

  • Chloe Norman

  • Dhruv Parekh

  • Emma M Parkin

  • Jaimin Patel

  • Scott E Regan

  • Clare Ross

  • Anthony J Rostron

  • Mohammad Saim

  • Anita K Simonds

  • Emma Skilton

  • Nigel Stallard

  • Michael Steiner

  • Rama Vancheeswaran

  • Joyce Yeung

  • Daniel F Mc Auley

Medical Centers

  • Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, Coventry, United Kingdom

  • Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom

  • Airway Innate Immunity Group, Wellcome Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom

  • Manchester Cancer Research Centre, University of Manchester, Manchester, United Kingdom

  • Population and Health Science Institute, NIHR Biomedical Research Centre, Newcastle University, Newcastle Upon Tyne, United Kingdom

  • Warwick Clinical Trials Unit, Warwick Medical School, Coventry, United Kingdom

  • Royal Brompton & Harefield Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

  • Sunderland Royal Hospital, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

  • Sunderland Royal Hospital, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, United Kingdom

  • Roslin Institute, University of Edinburgh, Midlothian, United Kingdom

  • Lane Fox Clinical Respiratory Physiology Centre, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom

  • Grange University Hospital, Aneurin Bevan University Health Board, Cwmbran, United Kingdom

  • Watford General Hospital, West Hertfordshire Hospitals NHS Trust, Watford, United Kingdom

  • Fairfield General Hospital, Pennine Acute Hospitals NHS Trust, Northern Care Alliance NHS Group, Bury, United Kingdom

  • Institute for Lung Health, NIHR BRC Respiratory Medicine, Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Infectious Diseases (ID)

Disease

  • Acute respiratory failure

  • Coronavirus disease

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Randomized

  • Adaptive

  • Open Label

  • Multiple Arm

  • Multicenteric

  • Controlled

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • National Institute For Health Research

Result

  • N/A