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: Exercise-Induced ATP7A, A Cu Transporter for SOD3, Restores Endothelial Dysfunction in Type2 Diabetes via Cysteine Oxidation of Protein Kinase G

Researchers

Presenter

  • Sudhahar Varadarajan

Principal Investigators

  • Kareem Abdelsaid

  • Harriet Boatwright

  • Malgorzata McMenamin

  • Philip Eaton

  • Masuko Ushio-Fukai

  • Tohru Fukai

Medical Centers

  • Queen Mary Univ of London, London

  • Vascular Biology Center, Medical College of Georgia at Augusta University, augusta, GA

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Vasodilation dysfunction

  • Diabetes

Biomarkers

  • Nucleoside diphosphate kinase A

  • Endothelial cell nitric oxide synthase

  • Superoxide dismutase

  • Superoxide Dismutase 3

Drug/Treatment

  • Nitric oxide

  • Cysteine Hydrochloride

Outcome

  • N/A


Study Design

  • N/A

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A