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2141 : How Well Does Ultrasound-assessed Synovitis in Reduced Joint Sets Predict the Response to Secukinumab in Patients with Active Psoriatic Arthritis and Inadequate Response to Conventional DMARDs? – Exploratory Results from a Phase 3b Study

Researchers

Presenter

  • Maria-Antonietta D'Agostino

Principal Investigators

  • Philip G Conaghan

  • Corine Gaillez

  • Esperanza Naredo

  • Peter mandl

  • Philippe Carron

  • Ladislav Šenolt

  • Javier Eduardo Rosa

  • Alejandra Lopez Rdz

  • Punit Goyanka

  • Braja Gopal Sahoo

  • Weibin Bao

  • Georg Schett

  • Maarten Boers

Medical Centers

  • Catholic University of the Sacred Heart, Rome, Italy

  • University of Leeds, Leeds, United Kingdom

  • Novartis AG, Basel, Switzerland

  • Hospital General Universitario Gregorio Marañόn and Complutense University

  • Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

  • Ghent University Hospital, Ghent, Belgium

  • Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Czech Republic

  • Hospital Aleman de Buenos Aires, Buenos Aires, Argentina

  • Dermatológico Country, PSOAPS Psoriasis Clinical and Research Centre, Guadalajara, Mexico

  • Novartis Healthcare Pvt. Ltd, Hyderabad, India

  • Novartis Pharmaceutical Corporation, East Hanover, NJ

  • Universitatsklinikum Erlangen, Erlangen, Germany

  • Amsterdam UMC, Vrije Universiteit Medical Center, Amsterdam, Netherlands

Locations

  • Italy

  • United Kingdom

  • Switzerland

  • Spain

  • Austria

  • Belgium

  • Czech Republic

  • Argentina

  • Mexico

  • India

  • United States

  • Germany

  • Netherlands

Companies

  • Novartis AG

Study Components

Therapeutic Area

  • Musculoskeletal

  • Dermatology

Disease

  • Psoriatic arthritis

Biomarkers

  • N/A

Drug/Treatment

  • secukinumab

Outcome

  • N/A

Study Design

  • Placebo Control

  • Double Blind/Blinded

  • Open Label

  • Controlled

Phase

  • III

Study Id's

  • NCT02662985

Sponsors

  • N/A

Result

  • N/A

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