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: Systems Analysis of Alzheimer’s Disease Pathway Dysregulation in Human Subjects is Recapitulated in 3D Cellular Models to Reveal P38 MAPK as a Therapeutic Target that Mitigates Tau Pathology

Researchers

Presenter

  • Pourya Naderi Yeganeh

Principal Investigators

  • Sang Su Kwak

  • Mehdi Jorfi

  • Luisa Quinti

  • Katjuša Koler

  • Younjung Choi

  • Joseph Park

  • Djuna K Von Maydell

  • Murat Centinbas

  • Ruslan I Sadreyev

  • Rudolph E. Tanzi

  • Winston Hide

  • Doo Yeon Kim

Medical Centers

  • Massachusetts General Hospital, Boston, MA

  • Massachusets Institute of Technology

  • Harvard Medical School, Boston, MA

  • University of Sheffi eld, UK

  • Beth Israel Deaconess Medical Center, Boston, MA

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Alzheimer's disease

Biomarkers

  • Mitogen-activated protein kinase

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A