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: A multimodal study on the effect of sex on Alzheimer's disease clinical and biomarker changes in adults with Down syndrome

Researchers

Presenter

  • M. Florencia Iulita

Principal Investigators

  • Eduard Vilaplana

  • Maria Carmona-Iragui

  • Bessy Benejam

  • Laura Videla

  • Isabel Barroeta

  • Susana Fernandez

  • Miren Altuna

  • Jordi Pegueroles

  • Victor Montal

  • Sílvia Valldeneu

  • Sandra Giménez

  • Sofía González-Ortiz

  • Laia Muñoz

  • Concepcion Padilla

  • Mateus Rozalem Aranha

  • Teresa Estellés

  • Ignacio Illán-Gala

  • Olivia Belbin

  • Natalia Valle Tamayo

  • Valle Camacho

  • Liam Wilson

  • Tiina Annus

  • Ricardo Osorio

  • Sebastián Videla

  • Sylvain Lehmann

  • Anthony J Holland

  • Henrik Zetterberg

  • Kaj Blennow

  • Daniel Alcolea

  • Jordi Clarimón

  • Shahid Zaman

  • Rafael Blesa

  • Alberto Lleó

  • Juan Fortea

Medical Centers

  • Clinical Research Support Unit. Bellvitge Biomedical Research Institute (IDIBELL) Department of Clinical Pharmacology, University of Barcelona

  • Cambridge Intellectual and Developmental Disabilities Research Group, Department of Psychiatry, University of Cambridge, Douglas House

  • CHU de Montpellier, INSERM, Université de Montpellier

  • Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Moelndal, Sweden

  • Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg

  • Centre of Biomedical Investigation Network for Neurodegenerative Diseases (CIBERNED)

  • Centre of Biomedical Investigation Network for Neurodegenerative Diseases (CIBERNED)

  • Center for Sleep and Brain Health, Department of Psychiatry, NYU Langone Health

  • Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau Biomedical Research Institute Sant Pau Universitat Autònoma de Barcelona, Spain

  • Department of Neurodegenerative Disease, UCL Institute of Neurology

  • Radiology Department, Parc de Salut, Hospital del Mar

  • Barcelona Down Medical Center, Catalan Foundation for Down Syndrome

  • Centre of Biomedical Investigation Network for Neurodegenerative Diseases (CIBERNED)

  • Women's Brain Project

  • Multidisciplinary Sleep Unit, Hospital de la Santa Creu i Sant Pau

  • CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III

  • Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Sweden

  • Cambridgeshire & Peterborough NHS Foundation Trust, Fulbourn Hospital,

  • Nuclear Medicine Department, Hospital de la Santa Creu i Sant Pau

  • Centre Médic Down de la Fundació Catalana Síndrome de Down

  • UK Dementia Research Institute

  • Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau Biomedical Research Institute Sant Pau Universitat Autònoma de Barcelona, Spain

Locations

  • Venezuela

  • United States

  • France

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Central Nervous System (CNS)

Disease

  • Alzheimer's disease

  • Down syndrome

  • Microtia hearing impairment and cleft palate

Biomarkers

  • Apolipoprotein E

  • Amyloid beta 42

  • Cerebrospinal fluid

  • Neurofilament-light chain

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Cross-Sectional

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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