// App-Quantinova.ai

: From brain volumes to subgroup classification in genetic mutation carriers for frontotemporal dementia: a cluster analysis in the GENFI study

Researchers

Presenter

  • Martina Bocchetta

Principal Investigators

  • Jennifer M Nicholas

  • Carolin Heller

  • Imogen J Swift

  • Georgia Peakman

  • David M Cash

  • Rhian S Convery

  • Lucy L Russell

  • David L Thomas

  • Juan Eugenio Iglesias

  • John C van Swieten

  • Lize C. Jiskoot

  • Harro Seelaar

  • Barbara Borroni

  • Daniela Galimberti

  • Raquel Sanchez-Valle

  • Robert Laforce

  • Fermin Moreno

  • Matthis Synofzik

  • Caroline Graff

  • Mario Masellis

  • Maria Carmela Tartaglia

  • James B Rowe

  • Rik Vandenberghe

  • Elizabeth Finger

  • Fabrizio Tagliavini

  • Alexandre Mendonca

  • Isabel Santana

  • Christopher Butler

  • Simon Ducharme

  • Alexander Gerhard

  • Adrian Danek

  • Johannes Levin

  • Markus Otto

  • Sandro Sorbi

  • Isabelle Le Ber

  • Florence Pasquier

  • Jonathan D Rohrer

Medical Centers

  • Clinique Interdisciplinaire de Mémoire, CHU de Québec/Université Laval/Hôpital de l’Enfant-Jésus

  • Karolinska Institutet, Department NVS, Division of Neurogeriatrics, Karolinska Institutet

  • Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology

  • Laboratory for Cognitive Neurology, Leuven Brain Institute, KU Leuven

  • Department of Clinical Neurological Sciences, University of Western Ontario

  • McGill University,

  • German Center for Neurodegenarative Diseases (DZNE)

  • Erasmus Medical Center,

  • University of Lisbon

  • Erasmus MC University Medical Center

  • LC Campbell Cognitive Neurology Research Unit, Sunnybrook Research Institute, University of Toronto

  • University of Milan

  • Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA

  • University of Florence,

  • Ludwig-Maximilians-Universität München,

  • Neurology Department, Hospital Clínic. Institut d'Investigacions Biomediques

  • German Center for Neurodegenerative Diseases (DZNE), Munich; Munich Cluster of Systems Neurology

  • Unit for Hereditary Dementia, Theme Inflammation and Aging, Karolinska University Hospital-Solna

  • University of Cambridge,

  • Erasmus MC,

  • Centre deréférence des démences rares ou précoces, IM2A, Département de Neurologie, AP-HP Hôpital Pitié-Salpêtrière

  • Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada

  • University of Ulm

  • Clinical Neurology, University of Oxford

  • CHU, CNR-MAJ, Labex Distalz, LiCENDLille

  • Centre for Neurodegenerative disorders, Neurology unit, Department of Clinical and Experimental Sciences, University of Brescia

  • INSERM 1172

  • Université de Lille, Inserm 1172, CHU Clinical and Research Memory Research Centre (CMRR) of Distalz

  • 4. UK Dementia Research Institute, Queen Square Institute of Neurology, University College London,

  • University of Duisburg-Essen

  • 3Sorbonne Universités, UPMC Université Paris 06, Inserm, CNRS, Institut du cerveau et la moelle (ICM) - Hôpital Pitié-Salpêtrière Paris France

  • Centro Hospitalar e Universitario de Coimbra, Portugal

  • Neuroradiological Academic Unit, UCL Queen Square Institute of Neurology

  • Wolfson Molecular Imaging Centre, University Of Manchester

  • Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London

  • Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Italy

  • Division of Neurology V/Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy

  • Centre for Neurology and Hertie-Institute for Clinical Brain Research Hoppe-Seyler-Str

  • Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom

  • AP-HP, Hôpital Pitié Salpêtrière

  • Hospital Universitario Donostia,

  • Dementia Research Centre at UCL Queen Square Institute of Neurology

  • 4. UK Dementia Research Institute, Queen Square Institute of Neurology, University College London,

Locations

  • Canada

  • Portugal

  • United States

  • Germany

  • Italy

  • France

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Central Nervous System (CNS)

Disease

  • Frontotemporal dementia

Biomarkers

  • Granulin precursor

  • Tau protein

  • Neurofilament-light chain

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved