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: Diet and APOE as moderators of the relationship between trimethylamine N-oxide and biomarkers of Alzheimer's disease and glial activation

Researchers

Presenter

  • John C. Thorstenson

Principal Investigators

  • Margo B. Heston

  • Katie R Zarbock

  • Cynthia M Carlsson

  • Corinne D. Engelman

  • Yuetiva Deming

  • Sterling C. Johnson

  • Tyler K. Ulland

  • Sanjay Asthana

  • Gwendlyn Kollmorgen

  • Ivonne Suridjan

  • Kaj Blennow

  • Henrik Zetterberg

  • Nathaniel A Chin

  • Federico E. Rey

  • Barbara B. Bendlin

Medical Centers

  • Cellular and Molecular Pathology PhD Program, University of Wisconsin School of Medicine and Public Health

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Geriatric Research Education and Clinical Center, William S. Middleton Veterans Hospital

  • Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine

  • Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin- Madison School of Medicine and Public Health

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Geriatric Research Education and Clinical Center, William S. Middleton Veterans Hospital

  • Geriatric Research, Education and Clinical Center, Madison VA Hospital

  • Univeristy of Wisconsin, Madison, WI

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

  • Roche Diagnostics International AG

  • Institute of Physiology and Neuroscience, University of Gothenburg

  • Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Sweden

  • Department of Population Health Sciences, University of Wisconsin

  • Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London

  • UK Dementia Research Institute

  • Wisconsin Alzheimer’s Institute, University of Wisconsin School of Medicine and Public Health

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Alzheimer's disease

Biomarkers

  • Apolipoprotein E

  • Chitinase 3 Like 1

  • Cerebrospinal fluid

Drug/Treatment

  • Carnitine

  • betaine

  • Choline bitartrate

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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