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5060 : Health-related quality of life (HRQoL) and pain in the MAGNITUDE study of niraparib (NIRA) with abiraterone acetate and prednisone (AAP) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) gene alterations.

Researchers

Presenter

  • Dana E. Rathkopf

Principal Investigators

  • Kim N. Chi

  • Shahneen Sandhu

  • Eleni Efstathiou

  • Gerhardt Attard

  • David Olmos

  • Ji Youl Lee

  • Eric Jay Small

  • Andrea Juliana Gomes

  • Marniza Saad

  • Elena Castro

  • Deniz Tural

  • Gary Mason

  • Katherine B. Bevans

  • Jeremiah Trudeau

  • Peter St. John Francis

  • George C. Wang

  • Angela Lopez-Gitlitz

  • Matthew Raymond Smith

Medical Centers

  • Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY

  • Institut Bergonie, Bordeaux, France

  • The University of British Columbia, Vancouver, BC, Canada

  • Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia

  • Houston Methodist Cancer Center, Houston, TX

  • Kings College London, London, United Kingdom

  • Hospital Universitario Doce de Octubre, Madrid, Spain

  • Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea,

  • University of California, San Francisco, San Francisco, CA

  • Liga Norte Riograndense Contra o Cncer, Natal, Brazil

  • University of Malaya, Kuala Lumpur, Malaysia

  • University Hospital Virgen de la Victoria (HUVV), Intercentre Clinical Management Unit (UGCI) of Medical Oncology, Málaga, Spain

  • Bakirkoy Sadi Konuk Training and Research Hospital, Istanbul, Turkey

  • Janssen Research and Development, LLC, Spring House, PA

  • Janssen Global Commercial Strategy Organization, Horsham, PA

  • Janssen Global Services, Raritan, NJ

  • Janssen Research & Development, LLC, Raritan, NJ

  • Janssen Research & Development, Los Angeles, CA

  • Massachusetts General Hospital Cancer Center, Boston, MA

Locations

  • United States

  • France

  • Canada

  • Australia

  • United Kingdom

  • Spain

  • Republic of South Korea

  • Brazil

  • Malaysia

  • Turkey

Companies

  • JB Medical Ltd.

Study Components

Therapeutic Area

  • Urology

  • Oncology (ONC)

Disease

  • Metastatic castration-resistant prostate cancer

Biomarkers

  • Hormone receptor

Drug/Treatment

  • CB-7598

  • Prednisone

  • Niraparib

Outcome

  • N/A

Study Design

  • Randomized

  • Placebo Control

Phase

  • III

Study Id's

  • NCT03748641

Sponsors

  • N/A

Result

  • N/A

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