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FRI0271 (2018) : Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle

Researchers

Presenter

  • D. Mauro

Principal Investigators

  • V. Tsang

  • I. Lucey-Clayton

  • F. Rivellese

  • S. Pagani

  • F. Alam

  • E. Pontarini

  • A. Nerviani

  • A. Pakozdi

  • R. Rajakariah

  • D. Pyne

  • T.J. Vyse

  • C. Pitzalis

  • M.J. Lewis

Medical Centers

  • Experimental Medicine and Rheumatology, Queen Mary University of London

  • Rheumatology Department, Mile End Hospital, Barts Health NHS Trust

  • Medical and Molecular Genetics, Kings College, London, London, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • NF-kappa-B inhibitor alpha

  • Interleukin-8

Drug/Treatment

  • Dimethyl fumarate

  • Resiquimod

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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