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: Continued long-term mepolizumab in severe eosinophilic asthma protects from asthma worsening versus stopping mepolizumab: COMET trial

Researchers

Presenter

  • Elisabeth H.D. Bel

Principal Investigators

  • Wendy C Moore

  • Oliver Kornmann

  • Claude Poirier

  • Nirihiro Kaneko

  • Steven G Smith

  • Neil Martin

  • Martyn J Gilson

  • Robert G Price

  • Eric S Bradford

  • Marc Humbert

Medical Centers

  • Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands

  • Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, United States of America

  • IKF Pneumologie Frankfurt, Clinical Research Centre Respiratory Diseases, Frankfurt, Germany,

  • Département de médecine, Service de pneumologie, Centre Hospitalier de l'Université de Montréal (CHUM, 1051 Sanguinet, Montreal, QC, Canada

  • Department of Sports Medicine Kameda Medical Center Kamogawa Japan

  • Respiratory Medical Franchise, GSK, Research Triangle Park, NC, United States,

  • Global Medical Affairs, GlaxoSmithKline and Institute for Lung Health, University of Leicester, Brentford, Middlesex and Leicester, United Kingdom

  • Respiratory Research and Development, GSK, Stockley Park, Uxbridge, Middlesex, United Kingdom,

  • Biostatistics, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom

  • Université Paris-Saclay and Assistance Publique- Hôpitaux de Paris, Service de Pneumologie et Soins Intensifs Respiratoires, Hôpital Bicêtre, Le Kremlin-Bicêtre and INSERM U999, Le Kremlin-Bicêtre, Paris, France

Locations

  • Netherlands

  • United States

  • Germany

  • Canada

  • Japan

  • United Kingdom

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Asthma

Biomarkers

  • N/A

Drug/Treatment

  • Mepolizumab

Outcome

  • N/A

Study Design

  • Randomized

  • Placebo Control

  • Double Blind/Blinded

  • Controlled

Phase

  • NA

Study Id's

  • NCT02555371

  • NCT01691859

  • NCT02135692

Sponsors

  • N/A

Result

  • N/A

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