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OC 63.4 : Little discrepancy of one-stage and chromogenic assays in a large international cohort of patients with non-severe hemophilia A and B (DYNAMO study)

Researchers

Presenter

  • A. Zwagemaker

Principal Investigators

  • F. Kloosterman

  • S. Gouw

  • S. Boyce

  • P. Brons

  • M. Cnossen

  • P. Collins

  • J. Eikenboom

  • C. Hay

  • S. Jackson

  • M. Kruip

  • B. Laros-van Gorkom

  • C. Male

  • L. Nieuwenhuizen

  • S. Shapiro

  • K. Fijnvandraat

  • M. Coppens

Medical Centers

  • Pediatric Hematology, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, the Netherlands, Amsterdam, Noord-Holland, Netherlands

  • Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands, Amsterdam, Noord-Holland, Netherlands

  • Department of Haematology, University Hospital Southampton, Southampton, United Kingdom, Southampton, England, United Kingdom

  • Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands, Nijmegen, Gelderland, Netherlands

  • Department of Pediatric Hematology, Sophia Children’s Hospital, Erasmus University Medical Center, Erasmus University Rotterdam, Rotterdam, The Netherlands, Rotterdam, Zuid-Holland, Netherlands

  • Medical School of Cardiff University, Cardiff, Wales, United Kingdom

  • 1VarmX, Leiden, The Netherlands. 2Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Leiden, Zuid-Holland, Netherlands

  • Department of Laboratory Haematology, Manchester Royal Infirmary, Manchester, United Kingdom

  • Adult Bleeding Disorders Program of BC - Adult Division St. Paul's Hospital, Vancouver, British Columbia, Canada, Vancouver, British Columbia, Canada

  • Department of Hepatology, Erasmus MC, University Medical Center Rotterdam, the Netherlands, Rotterdam, Netherlands

  • Radboud University Medical Center, Nijmegen, the Netherlands; Hemophilia Treatment Center, Nijmegen-Eindhoven-Maastricht, the Netherlands, Nijmegen, Gelderland, Netherlands

  • Medical University of Vienna, Vienna, Austria, Vienna, Wien, Austria

  • Department of Hematology, Máxima Medical Center, Eindhoven, Netherlands; Radboud university medical center, Hemophilia Treatment Center, Nijmegen – Eindhoven – Maastricht, Netherlands, Eindhoven, Noord-Brabant, Netherlands

  • Oxford University NHS Foundation Trust, Oxford, United Kingdom

  • Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands, Amsterdam, Noord-Holland, Netherlands

  • Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Amsterdam, Noord-Holland, Netherlands

Locations

  • Netherlands

  • United Kingdom

  • Canada

  • Austria

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Hemophilia

Biomarkers

  • N/A

Drug/Treatment

  • FVIII

Outcome

  • N/A


Study Design

  • Multinational

  • Multicenteric

  • Cohort

Phase

  • NA

Study Id's

  • NCT03623295

Sponsors

  • N/A

Result

  • N/A