// App-Quantinova.ai

P1033 : A PHASE 2 STUDY OF THE LSD1 INHIBITOR IMG-7289 (BOMEDEMSTAT) FOR THE TREATMENT OF ESSENTIAL THROMBOCYTHEMIA (ET)

Researchers

Presenter

  • Francesca Palandri

Principal Investigators

  • Tara Cochrane

  • Courtney Tate

  • Steven W. Lane

  • Stephen R. Larsen

  • Aaron T. Gerds

  • Anna B. Halpern

  • Jake Shortt

  • James M. Rossetti

  • Kristen M. Pettit

  • James Liang

  • Adam Mead

  • Monia Marchetti

  • Alessandro Vannucchi

  • Andrew Wilson

  • Joachim R. Gthert

  • Merit Hanna

  • Amber Jones

  • Jennifer Peppe

  • Georges Natsoulis

  • Ty McClure

  • Wan-Jen Hong

  • William S. Stevenson

  • Claire N. Harrison

  • Moshe Talpaz

  • Nicola Vianelli

  • Hugh Young Rienhoff Jr

Medical Centers

  • Department of Haematology,Royal Adelaide Hospital and SA Pathology,Adelaide,Australia

  • Monash Haematology,Monash Health,Clayton,А

  • Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • Middlemor

  • Middlemore Clinical Trials,Auckland,Nuova Zelanda

  • Middlemore Clinical Trials,Auckland,Nouvelle-zélande

  • Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • University of Florence, AOU Careggi, CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms,Florence,Italia

  • Department of Medicine/Division of Hematology, University of Washington, Seattle, WA

  • Cleveland Clinic Taussig Cancer Institute, Cleveland, OH

  • Guy's and St Thomas' NHS Foundation Trust,London,Reino Unido

  • Monash Health, Monash University, Clayton, Australia

  • Institute of Haematology,Royal Prince Alfred Hospital,Sydney,Australie

  • Guy's and St. Thomas' NHS Foundation Trust,London,Vereinigtes Königreich

  • A. Seràgnoli", Sant'Orsola-Malpighi University Hospital,Bologna,Italia

  • Guy's and St

  • UPMC Hillman Cancer Center

  • A. Seragnoli", Azienda

  • University College London Hospitals NHS Foundation Trust,London,Vereinigtes Königreich

  • Institute of Academic Surgery, Royal Prince Alfred Hospital, Camperdown, Australia

  • QIMR Berghofer Medical Research Institute, Brisbane, Sydney, Australia

  • A. Seràgnoli", Sant'Orsola-Malpighi University Hospital,Bologna,Italia

  • Cleveland Clinic Taussig Cancer Institute, Cleveland, OH

  • Department of Haematology,Royal Adelaide Hospital and SA Pathology,Adelaide,Australia

  • Department of Surgery, Westgerman Cancer Center, University Hospital Essen, Essen, Germany

  • Department of Haematology,Royal Adelaide Hospital and SA Pathology,Adelaide,Australia

  • QIMR Berghofer Medical Research Institute, Brisbane, Sydney, Australia

  • North Shore Hospital. Waitemata District Health Board,Auckland,Neuseeland

  • Department of Internal Medicine Division of Rheumatology

  • Imago BioSciences, Inc.,South San Francisco,United States

  • Genetics,Imago BioSciences,South San Francisco,Stati Uniti

  • Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI

  • IGF Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • Monash Haematology,Monash Health,Clayton,Australië

  • A. Seragnoli", Azienda Ospedaliero-Universitaria di Bologna,Bologna,Italia

  • Imago BioSciences, Inc.,South San Francisco,États-unis

  • QIMR Berghofer Medical Research Institute, Brisbane, Sydney, Australia

  • QIMR Berghofer Medical Research I

  • Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales, Australia

  • Monash Haematology,Monash Health,Clayton,Australië

  • Department of Medicine/Division of Hematology, University of Washington, Seattle, WA

  • UPMC Hillman Cancer Center,Pittsburg,Stati Uniti

  • Monash Haematology,Monash Health,Clayton,Australië

  • Institute of Haematology,Royal Prince Alfred Hospital,Sydney,Australie

  • Cleveland Clinic Taussig Cancer Institute,Cleveland,Verenigde Staten

  • Institute of Hematology an

  • Monash Haematology,Monash Health,Clayton,Australië

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Royaume-uni

  • Azienda Opedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  • A. Seràgnoli", Sant'Orsola-Malpigh

  • University of Florence,

  • UPMC Hillman Cancer Center,Pittsburgh,Verenigde Staten

  • North Shore Hospital. Waitemata District Health Board,Auckland,Neuseeland

  • Guy's and St. Thomas' NHS Foundation Trust,London,Vereinigtes Königreich

  • Department of Haematology, Gold Coast University Hospital, Southport, Australia

  • Middlemore Clinical Trials,Auckland,Nuova Zelanda

  • University of Florence, AOU Careggi, CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms,Florence,Italia

  • Genetics,Imago BioSciences,South San Francisco,Stati Uniti

  • Department of Medicine, T

  • UPMC Hillman Cancer Center,Pittsburgh,Verenigde Staten

  • Department of Haematology, Gold Coast University Hospital, Southport, Australia

  • Department of Hematology,West German Cancer Center (WTZ), University Hospital Essen,Essen,Allemagne

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Vereinigtes Königreich

  • Department of Hematology,West German Cancer Center (WTZ), University Hospital Essen,Essen,Allemagne

  • A. Seràgnoli", Sant'Orsola-Malpighi University Hospital,Bologna,Italia

  • Azienda Opedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  • MRC Weatherall Institute of Molecular Medicine, University of Oxford,Oxford,Royaume-uni

  • Department of Medicine/Division of Hematology, University of Washington, Seattle, WA

  • University of Florence, AOU Careggi, CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms,Florence,Italia

  • Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI

  • Middlemore Clinical Trials,Auckland,Новая Зеландия

  • A. Seragnoli", Azienda Ospedaliero-Universitaria di Bologna,Bologna,Italia

  • Imago BioSciences, Inc.,South San Francisco,États-unis

  • Middlemore Clinical Trials,Auckland,Nuova Zelanda

  • Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI

  • Department of Hematology,West German Cancer Center (WTZ), University Hospital Essen,Essen,Allemagne

  • Genetics,Imago BioSciences,South San Francisco,Stati Uniti

  • Department of...

  • Cleveland Clinic Taussig Cancer Institute,Cleveland,Verenigde Staten

  • Azienda Opedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  • Cleveland Clinic Taussig Cancer Institute, Cleveland, OH

  • UPMC Hillman Cancer Center,Pittsburg,Stati Uniti

  • MRC Weatherall Institute of Molecular

  • Hematology,University College London Hospitals (UCLH) NHS Foundation Trust,London,Royaume-uni

  • Guy's And St Thomas NHS Foundation Trust, London, United Kingdom

  • Kolling Institute of Medical Research, Royal North Shore Hospital,S

  • North Shore Hospital. Waitemata District Health Board,Auckland,Neuseeland

  • A. Seragnoli", Azienda Ospedaliero-Universitaria di Bologna,Bologna,Italia

  • Department of Medicine/Division of Hematology, University of Washington, Seattle, WA

  • Department of Haematology,Royal Adelaide Hospital and S

  • Middlemore Clinical Trials,Auckland,Nuova Zelanda

  • Imago BioSciences, Inc.,South San Francisco,United States

  • Guy's and St Thomas' NHS Foundation Trust,London,Royaume-uni

  • North Shore Hospital. Waitemata District Health Board,Auckland,Neuseeland

  • Institute of Hematology an

  • Department of Haematology, Gold Coast University Hospital, Southport, Australia

  • UPMC Hillman Cancer Center,Pittsburgh,Verenigde Staten

  • UPMC Hillman Cancer Center,Pittsburg,Stati Uniti

  • Institute of Haematology,Royal Prince Alfred

  • Middlemore Clinical Trials,Auckland,Nuova Zelanda

  • North Shore Hospital. Wai

  • University College Hospital, NHS Foundati

  • Middlemore Clinical Trials,Auckland,新西兰

  • Azienda Opedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  • King's College Hosptial NHS Foundation Trust, London, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust,London,Reino Unido

  • QIMR Berghofer Medical Research Institute, Brisbane, Sydney, Australia

  • Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Ces

  • North Shore Hospital. Waitemata District Health Board,Auckland,Neuseeland

  • Cleveland Clinic Taussig Cancer Institute, Cleveland, OH

Locations

  • Italy

  • Australia

  • Canada

  • United States

  • New Zealand

  • United Kingdom

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Oncology (ONC)

Disease

  • Essential thrombocythemia

Biomarkers

  • Lysine-specific histone demethylase 1A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • II

Study Id's

  • NCT04254978

  • NCT03136185

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved