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S259 : DUAL ANTIGEN TARGETING WITH CO-TRANSDUCED CD19/22 CAR T CELLS FOR RELAPSED/REFRACTORY ALL

Researchers

Presenter

  • Sara Ghorashian

Principal Investigators

  • Rachel Richardson

  • Kyvi Nguyen

  • Craig Terris

  • Jenny Yeung

  • Jan Chu

  • Lindsey Williams

  • Kaye Ko

  • Chloe Walding

  • Kelly Watts

  • Sarah Inglott

  • Stuart Adams

  • Emma Gravett

  • Kimberly Gilmour

  • Alka Lal

  • Bilyana Popova

  • Andre Lopes

  • Yenting Ngai

  • Eva Kokalaki

  • Kanchan Rao

  • Robert Chiesa

  • Juliana Silva

  • Khushnuma Mullanfiroze

  • Arina Lazareva

  • Denise Bonney

  • Robert Wynn

  • Martin Pule

  • Rachael Hough

  • Persis Amrolia

Medical Centers

  • Autolus Ltd,London,Reino Unido

  • Cell Therapy and Immunology,Great Ormond St Children's Hospital,London,Regno Unito

  • UCL Cancer Trials Centre,London,Reino Unido

  • Haematology,Great Ormond St Children's Hospital,London,Reino Unido

  • Dept. Imaging,University College London Hospitals,London,Regno Unito

  • Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, United Kingdom

  • Molecular and Cellular Immunology Section, UCL Great Ormond Street Institute of Child Health, London, ENG, United Kingdom

  • Cell Therapy and Immunology,Great Ormond St Children's Hospital,London,Regno Unito

  • Bone Marrow Transplant, Great Ormond Street Hospital, London, United Kingdom

  • Autolus Ltd,London,Соединённое Королевство

  • Haematology,University College London Hospital NHS Trust,London,Vereinigtes Königreich

  • Autolus Ltd,London,Royaume-uni

  • Blood and Marrow Transplant,Royal

  • Dept. Imaging,University College London Hospitals,London,Regno Unito

  • Haematology,University College London Hospital NHS Trust,London,Royaume-uni

  • UCL Cancer Trials Centre,London,Vereinigtes Königreich

  • Molecular and Cellular Immunology Section, UCL Great Ormond Street Institute of Child Health, London, ENG, United Kingdom

  • Blood and Marrow Transplant,Royal Manchester Children's Hospital,Manchester,Royaume-uni

  • UCL Cancer Trials Centre,London,Reino Unido

  • Molecular and Cellular Immunology,UCL Great Ormond St Institute of Child Health,London,Vereinigtes Königreich

  • CRUK and UCL Cancer Trials Centre, London, United Kingdom

  • Autolus Ltd,London,Reino Unido

  • Haematology,Great Ormond St Children's Hospital,London,Reino Unido

  • Haematology,Great Ormond St Children's Hospital,London,Reino Unido

  • Autolus Ltd,London,Vereinigtes Königreich

  • University College London Hospitals NHS Trust, London, United Kingdom

  • Bone Marrow Transplant, Great Ormond Street Hospital, London, United Kingdom

  • Cell Therapy and Immunology,Great Ormond St Children's Hospital,London,Regno Unito

  • Autolus Limited, London, United Kingdom

  • Haematology,Great Ormond St Children's Hospital,London,Vereinigtes Königreich

  • UCL Cancer Trials Centre,London,Royaume-uni

  • Autolus Ltd,London,Storbritannien

  • Hemat

  • Haematology,Great Ormond St Children's Hospital,London,Reino Unido

  • Cell Therapy and Immunology,Great Ormond St Children's

  • Molecular and Cellular Immunology,UCL Great Ormond St Institute of Child Health,London,Vereinigtes Königreich

  • Cancer Research UK &a

  • Autolus Ltd,London,Verenigd Koninkrijk

  • Blood and Marrow Transplant,Royal Manchester Children's Hospital,Manchester,Royaume-uni

  • Blood and Marrow Transplant,Royal Manchester Children's Hospital,Manchester,Royaume-uni

  • Cell Therapy and Immunology,Great Ormond St Children's Hospital,London,Regno Unito

  • Haematology, Great Ormond Street Childrens Hospital, London, United Kingdom

  • Cancer Research UK &a

Locations

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Coxsackie Virus And Adenovirus Receptor

  • Cluster of Differentiation 19

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • tisagenlecleucel-t

  • fludarabine tablet

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I

Study Id's

  • NCT02443831

Sponsors

  • N/A

Result

  • N/A

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