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S294 : LONG-TERM SAFETY AND EFFICACY OF CAPLACIZUMAB FOR ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA (ATTP): THE POST-HERCULES STUDY

Researchers

Presenter

  • Marie Scully

Principal Investigators

  • Javier de la Rubia

  • Katerina Pavenski

  • Ara Metjian

  • Paul Knbl

  • Flora Peyvandi

  • Spero Cataland

  • Paul Coppo

  • Johanna A Kremer Hovinga

  • Rui De Passos Sousa

  • Filip Callewaert

  • Sriya Gunawardena

  • Julie Lin

Medical Centers

  • Division of Hematology, Department of Medicine,University of Colorado–Anschutz Medical Center,Denver, CO,Stati Uniti

  • Sanofi, Cambridge, United States

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Sanofi, Lisbon, Portugal

  • Sanofi, Diegem, Belgium

  • Department of Medicine 1, Division of Hematology and Hemostasis,Medical University of Vienna,Vienna,Österreich

  • Department of Hematology, Reference Center for Thrombotic Microangiopathies (CNR-MAT), Saint-Antoine University Hospital, AP-HP, Paris, France

  • Sanofi, Diegem, Belgium

  • Division of Hematology, Department of Medicine,University of Colorado–Anschutz Medical Center,Denver, CO,Stati Uniti

  • Department of Internal Medicine, The Ohio State University, Columbus, OH

  • Sanofi, Cambridge, MA

  • Department of Hematology, Reference Center for Thrombotic Microangiopathies (CNR-MAT), Saint-Antoine University Hospital, AP-HP, Paris, France

  • Department of Hematology, Reference Center for Thrombotic Microangiopathies (CNR-MAT), Saint-Antoine University Hospital, AP-HP, Paris, France

  • Dept. Haematology,University College London Hospitals,London,Vereinigtes Königreich

  • Sanofi,Lisbon,Португалия

  • Department of Internal Medicine, The Ohio State University, Columbus, OH

  • Division of Hematology, Department of Medicine,University of Colorado–Anschutz Medical Center,Denver, CO,Stati Uniti

  • Sanofi,Cambridge, MA,Estados Unidos

  • IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milano, Italy

  • Hematology and Central Hematology Laboratory, Inselspital, University Hospital of Bern, Bern, Switzerland

  • Sanofi, Diegem, Belgium

  • Department of Rheumatology, University College London, London, UK

  • Department I

  • Sanofi, Diegem, Belgium

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Departments of Medicine and Laboratory Medicine,St. Michael's Hospital,Toronto, ON,Canada

  • Hematology Department, Internal Medicine, School of Medicine and Dentistry, Catholic University of Valencia, Valencia, Spain

  • Hematology Department, Internal Medicine,School of Medicine and Dentistry, Catholic University of Valencia,Valencia,Spagna

  • Department of Internal Medicine, The Ohio State University, Columbus, OH

  • Hematology Department, Intern

  • Sanofi,Cambridge, MA,États-unis

  • Division of Neurology, Department of Medicine

  • Department of Haematological Medicine, King's College London, London, United Kingdom

  • Dept. of Medicine I, Div. of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria

  • Sanofi,Cambridge, MA,Stati Uniti

  • Department of Medicine 1, Division of Hematology and Hemostasis,Medical

  • Sanofi,Diegem,Bélgica

  • Department of Internal Medicine, The Ohio State University, Columbus, OH

  • Hematology Department, Internal Medicine,School of Medicine and Dentistry, Catholic University of Valencia,Valencia,Spagna

  • Hematology and Central Hematology Laboratory, Inselspital, University Hospital of Bern, Bern, Switzerland

  • Department of Rheumatology, University College London, London, UK

  • Hematology,University College London Hospitals,London,Royaume-uni

  • Sanofi, Lisbon, Portugal

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Departments of Medicine and Laboratory M

  • Departments of Medicine and Laboratory Medicine,St. Michael's Hospital,Toronto, ON,Canada

  • Hematology and Central Hematology Laboratory, Inselspital, University Hospital of Bern, Bern, Switzerland

  • Department of Internal Medicine,Ohio State University,Columbus, OH,Vereinigte Staaten

  • Sanofi,Cambridge, MA,Vereinigte Staaten

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore

  • Sanofi, Lisbon, Portugal

  • Sanofi,Cambridge, MA,Vereinigte Staaten

  • Department of Medicine 1, Division of Hematology and Hemostasis,Medical University of Vienna,Vienna,Österreich

  • Sanofi,Diegem,Belgien

Locations

  • United Kingdom

  • Venezuela

  • Canada

  • Brazil

  • United States

  • Austria

  • Italy

  • France

  • Switzerland

  • Portugal

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Genetic Disorder

Disease

  • Thrombotic thrombocytopenic purpura

Biomarkers

  • N/A

Drug/Treatment

  • ALX-0081

Outcome

  • N/A

Study Design

  • Open Label

Phase

  • III

Study Id's

  • NCT02878603

Sponsors

  • N/A

Result

  • N/A

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